acetylcholine receptor subunit alpha-like [Drosophila takahashii].

LOCUS       XP_044251721             799 aa            linear   INV 09-DEC-2024
ACCESSION   XP_044251721
VERSION     XP_044251721.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_044395786.2
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..799
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..799
                     /product="acetylcholine receptor subunit alpha-like"
                     /calculated_mol_wt=87516
     Region          25..243
                     /region_name="LGIC_ECD_nAChR_proto_alpha-like"
                     /note="extracellular domain of nicotinic acetylcholine
                     receptor subunit alpha-like found in protostomia; cd19031"
                     /db_xref="CDD:349832"
     Site            order(61,63,69..70,77,99,101,110..111,113,115..116,120,
                     122..123,127..129,131,141,143,145,149,171,240)
                     /site_type="other"
                     /note="pentamer interface [polypeptide binding]"
                     /db_xref="CDD:349832"
     Region          150..164
                     /region_name="Cys-loop"
                     /note="Cys-loop [structural motif]"
                     /db_xref="CDD:349832"
     Region          242..>331
                     /region_name="LGIC_TM_nAChR"
                     /note="transmembrane domain of nicotinic acetylcholine
                     receptor (nAChR); cd19064"
                     /db_xref="CDD:349866"
     Region          242..266
                     /region_name="TM1 helix"
                     /note="TM1 helix [structural motif]"
                     /db_xref="CDD:349866"
     Site            order(274,277,281,284..285,288,292,320,323,326..327,
                     329..331)
                     /site_type="other"
                     /note="pentamer interface [polypeptide binding]"
                     /db_xref="CDD:349866"
     Region          274..295
                     /region_name="TM2 helix"
                     /note="TM2 helix [structural motif]"
                     /db_xref="CDD:349866"
     Region          306..328
                     /region_name="TM3 helix"
                     /note="TM3 helix [structural motif]"
                     /db_xref="CDD:349866"
     Region          <687..764
                     /region_name="Neur_chan_memb"
                     /note="Neurotransmitter-gated ion-channel transmembrane
                     region; pfam02932"
                     /db_xref="CDD:460753"
     CDS             1..799
                     /gene="nAChRalpha3"
                     /coded_by="XM_044395786.2:988..3387"
                     /db_xref="GeneID:108054798"
ORIGIN      
        1 mkwfqvtidm ilvlsfisss tanpdakrly ddllsnynkl vrpvvnvtda ltvriklkls
       61 qlidvnlknq imttnlwveq swydyklkwe pkeyggveml hvpsdhiwrp divlynnadg
      121 nfevtlatka tlnytgrvew rppaiykssc eidveyfpfd eqtcvmkfgs wtydgfqvdl
      181 rhidelngtn vvevgvdlse fytsvewdil evpavrnekf ytccdepyld itfnitmrrk
      241 tlfytvnlii pcmgisflti lvfylpsdsg ekvslsisil lsltvfflll aeiipptslv
      301 vpllgkfvlf tmildtfsic vtvlvlnihf rspqthtmap wvrtvfinql prflvmrrpl
      361 ypisemikss rrlmvrtcng lelrdqippl pppvalsrmh hspkttsrst sphlqhraqt
      421 ynlmdecgmg gmggmggggg astitghlss lypptmstan qqtsttssli daqyhnqyqq
      481 tggslldhpl tptkfrqmts tssqtgqngn gngggngggg ggygghnlyr qqsscsanfs
      541 plpqhahqah astttsdlgm anpnvikstt tvnsvatast laesccsgti qihqgmgaga
      601 acqssellhh qqlhhqqmhh qqqqqqyqqr pttsaaaaaa aaaaaaaagg gpstsaaaaa
      661 aaaaaaagtp ppppppagvc dilpacqreg gphccsgrgn vrqrwhtcpe lhkamdgvty
      721 iadqtrkeee strvkedwky vamvldrlfl wiftiavvvg tagiilqapt lydtrmpidi
      781 klseiastta kpnvarpvl