sepiapterin reductase [Drosophila takahashii].

LOCUS       XP_044251000             261 aa            linear   INV 09-DEC-2024
ACCESSION   XP_044251000
VERSION     XP_044251000.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_044395065.2
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..261
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..261
                     /product="sepiapterin reductase"
                     /calculated_mol_wt=28874
     Region          7..258
                     /region_name="Rossmann-fold NAD(P)(+)-binding proteins"
                     /note="A large family of proteins that share a
                     Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The
                     NADB domain is found in numerous dehydrogenases of
                     metabolic pathways such as glycolysis, and many other
                     redox enzymes. NAD binding involves numerous...; cl21454"
                     /db_xref="CDD:473865"
     Site            order(13..18,41..43,68..70,99..101,125,151..153,166,170,
                     196..199,201..204)
                     /site_type="other"
                     /note="NADP binding site [chemical binding]"
                     /db_xref="CDD:187625"
     Site            order(79,116..117,119..120,123..124,127..128,131..132,135,
                     155..157,164..165,167..168,172,175..176,179..180,182..184)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:187625"
     Site            order(126,153,166,170)
                     /site_type="active"
                     /db_xref="CDD:187625"
     CDS             1..261
                     /gene="Sptr"
                     /coded_by="XM_044395065.2:116..901"
                     /db_xref="GeneID:123003225"
ORIGIN      
        1 mdlkqrtyll vtgasrgigr efaqqlakri aaegsvvvll grnqplleea raqivasvpe
       61 lpvhtyslel esaktedfaq ilessaaqks fqraivihna gtvgdtskra keigdtsflq
      121 syyhtnvfsa islncefmrv frgipklvvn lstlaaiapi ssmahyctvk aaremyfrvl
      181 ateesaeetl vlnyapgvid tqmtvqvqre ahdpavvamf reqreaktml ttaqtterfi
      241 qilearkfks gdhvdyrdgq t