probable citrate synthase, mitochondrial isoform X2 [Drosophila

LOCUS       XP_022226639             464 aa            linear   INV 14-MAY-2021
            obscura].
ACCESSION   XP_022226639
VERSION     XP_022226639.1
DBLINK      BioProject: PRJNA728747
DBSOURCE    REFSEQ: accession XM_022370947.2
KEYWORDS    RefSeq.
SOURCE      Drosophila obscura
  ORGANISM  Drosophila obscura
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_024542752.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Drosophila obscura Annotation
                                           Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.6
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Drosophila obscura"
                     /isolate="BZ-5 IFL"
                     /db_xref="taxon:7282"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="whole fly"
                     /dev_stage="Adult fly"
                     /geo_loc_name="Serbia: Babin Zub"
                     /collection_date="2017"
     Protein         1..464
                     /product="probable citrate synthase, mitochondrial isoform
                     X2"
                     /calculated_mol_wt=51502
     Region          34..461
                     /region_name="ScCit1-2_like"
                     /note="Saccharomyces cerevisiae (Sc) citrate synthases
                     Cit1-2_like. Citrate synthases (CS) catalyzes the
                     condensation of acetyl coenzyme A (AcCoA) with
                     oxaloacetate (OAA) to form citrate and coenzyme A (CoA),
                     the first step in the citric acid cycle (TCA or...;
                     cd06105"
                     /db_xref="CDD:99858"
     Site            order(72..73,76..82,167,171,174,266,271,274..275,278..279,
                     282..284,288,295..296,299..301,349,446..454)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:99858"
     Site            order(74,266,270,300..303,305,308,342..349,352,357,398,
                     401,403,425,429,446,449)
                     /site_type="active"
                     /db_xref="CDD:99858"
     Site            order(74,300..302,305,308,342..349,352,398,401,403,446)
                     /site_type="other"
                     /note="coenzyme A binding site [chemical binding]"
                     /db_xref="CDD:99858"
     Site            order(74,266,270,301..302,342..343,345..349,357,401,429)
                     /site_type="other"
                     /note="citrylCoA binding site [chemical binding]"
                     /db_xref="CDD:99858"
     Site            order(266,270,302..303,348..349,357,403,425,429,449)
                     /site_type="other"
                     /note="oxalacetate/citrate binding site [chemical
                     binding]"
                     /db_xref="CDD:99858"
     Site            order(302,348,403)
                     /site_type="active"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:99858"
     CDS             1..464
                     /gene="LOC111076900"
                     /coded_by="XM_022370947.2:148..1542"
                     /db_xref="GeneID:111076900"
ORIGIN      
        1 mslyrisark lveaqklpnv gsyvrlisad grslrdvlna kvpeeqervk nfrkqhgatk
       61 lgettidmmy ggmrgikalv tetsvldade girfrglsip ecqkvlpaap ggteplpegl
      121 fwllltgevp sqaqvqqlsr ewaeraalpq hvvtmlnnmp tslhpmsqla aavtalnhds
      181 kfakaysegv hkskyweyvy edsmdliakl pvvaatiycn tyrggkgsrs idssldwsan
      241 fvkmlgydna qftelmrlyl tihsdheggn vsahtvhlvg salsdpylsf aagmnglagp
      301 lhglanqevl vwlrklqkea gnnpseeqlk eyiwktlksg qvvpgyghav lrktdprytc
      361 qrefalkhlp edelfqlvsk iykvvppilt etgkvknpwp nvdahsgvll qyfgmkemny
      421 ytvlfgvsra lgvlaslvwd ralglpierp ksystdllvk mvqk