probable citrate synthase, mitochondrial isoform X1 [Drosophila

LOCUS       XP_022226637             517 aa            linear   INV 14-MAY-2021
            obscura].
ACCESSION   XP_022226637
VERSION     XP_022226637.2
DBLINK      BioProject: PRJNA728747
DBSOURCE    REFSEQ: accession XM_022370945.2
KEYWORDS    RefSeq.
SOURCE      Drosophila obscura
  ORGANISM  Drosophila obscura
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_024542752.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On May 14, 2021 this sequence version replaced XP_022226637.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Drosophila obscura Annotation
                                           Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.6
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Drosophila obscura"
                     /isolate="BZ-5 IFL"
                     /db_xref="taxon:7282"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="whole fly"
                     /dev_stage="Adult fly"
                     /geo_loc_name="Serbia: Babin Zub"
                     /collection_date="2017"
     Protein         1..517
                     /product="probable citrate synthase, mitochondrial isoform
                     X1"
                     /calculated_mol_wt=57369
     Region          87..514
                     /region_name="ScCit1-2_like"
                     /note="Saccharomyces cerevisiae (Sc) citrate synthases
                     Cit1-2_like. Citrate synthases (CS) catalyzes the
                     condensation of acetyl coenzyme A (AcCoA) with
                     oxaloacetate (OAA) to form citrate and coenzyme A (CoA),
                     the first step in the citric acid cycle (TCA or...;
                     cd06105"
                     /db_xref="CDD:99858"
     Site            order(125..126,129..135,220,224,227,319,324,327..328,
                     331..332,335..337,341,348..349,352..354,402,499..507)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:99858"
     Site            order(127,319,323,353..356,358,361,395..402,405,410,451,
                     454,456,478,482,499,502)
                     /site_type="active"
                     /db_xref="CDD:99858"
     Site            order(127,353..355,358,361,395..402,405,451,454,456,499)
                     /site_type="other"
                     /note="coenzyme A binding site [chemical binding]"
                     /db_xref="CDD:99858"
     Site            order(127,319,323,354..355,395..396,398..402,410,454,482)
                     /site_type="other"
                     /note="citrylCoA binding site [chemical binding]"
                     /db_xref="CDD:99858"
     Site            order(319,323,355..356,401..402,410,456,478,482,502)
                     /site_type="other"
                     /note="oxalacetate/citrate binding site [chemical
                     binding]"
                     /db_xref="CDD:99858"
     Site            order(355,401,456)
                     /site_type="active"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:99858"
     CDS             1..517
                     /gene="LOC111076900"
                     /coded_by="XM_022370945.2:16..1569"
                     /db_xref="GeneID:111076900"
ORIGIN      
        1 myfsrcltpd vvlhlqcrtl akksvrdakn llreilrapl eeevqektvv qavakpqaar
       61 dggpdslqkl pnvgsyvrli sadgrslrdv lnakvpeeqe rvknfrkqhg atklgettid
      121 mmyggmrgik alvtetsvld adegirfrgl sipecqkvlp aapggteplp eglfwllltg
      181 evpsqaqvqq lsrewaeraa lpqhvvtmln nmptslhpms qlaaavtaln hdskfakays
      241 egvhkskywe yvyedsmdli aklpvvaati ycntyrggkg srsidssldw sanfvkmlgy
      301 dnaqftelmr lyltihsdhe ggnvsahtvh lvgsalsdpy lsfaagmngl agplhglanq
      361 evlvwlrklq keagnnpsee qlkeyiwktl ksgqvvpgyg havlrktdpr ytcqrefalk
      421 hlpedelfql vskiykvvpp iltetgkvkn pwpnvdahsg vllqyfgmke mnyytvlfgv
      481 sralgvlasl vwdralglpi erpksystdl lvkmvqk