protein kinase shaggy isoform X1 [Drosophila obscura].


LOCUS       XP_022220050             863 aa            linear   INV 14-MAY-2021
ACCESSION   XP_022220050
VERSION     XP_022220050.2
DBLINK      BioProject: PRJNA728747
DBSOURCE    REFSEQ: accession XM_022364358.2
KEYWORDS    RefSeq.
SOURCE      Drosophila obscura
  ORGANISM  Drosophila obscura
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_024542752.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On May 14, 2021 this sequence version replaced XP_022220050.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Drosophila obscura Annotation
                                           Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.6
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..863
                     /organism="Drosophila obscura"
                     /isolate="BZ-5 IFL"
                     /db_xref="taxon:7282"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="whole fly"
                     /dev_stage="Adult fly"
                     /geo_loc_name="Serbia: Babin Zub"
                     /collection_date="2017"
     Protein         1..863
                     /product="protein kinase shaggy isoform X1"
                     /calculated_mol_wt=87219
     Region          336..627
                     /region_name="STKc_GSK3"
                     /note="The catalytic domain of the Serine/Threonine
                     Kinase, Glycogen Synthase Kinase 3; cd14137"
                     /db_xref="CDD:271039"
     Site            order(346..350,354,367,369,380,394,416..419,422,424..425,
                     465,467,469..470,472,484,487,498,500..503,505,543)
                     /site_type="active"
                     /db_xref="CDD:271039"
     Site            order(346..349,354,367,369,394,416..419,422,467,469..470,
                     472,484)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:271039"
     Site            order(350..351,496..504,512..513,544..548,550..551,555,
                     575..578)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:271039"
     Site            order(380,424,465,467,487,498,500..503,505,543)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:271039"
     Site            order(483..493,495..505)
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:271039"
     Site            order(512,547..548,550..551,554..555,575..580)
                     /site_type="other"
                     /note="axin binding site [polypeptide binding]"
                     /db_xref="CDD:271039"
     CDS             1..863
                     /gene="LOC111072462"
                     /coded_by="XM_022364358.2:45..2636"
                     /db_xref="GeneID:111072462"
ORIGIN      
        1 mavprvrkvv rvvrkkkrat gtgtgssasi ndasesdggg agadtatssg aasgrqnsis
       61 ipismdeiea kaaaaasaag asssrpwtpm pprkppakaa kikrrpstgg gsgggsasgn
      121 gsivgaasak gsaaasaaae aeqrrqrkdk krrsssdsnd sddnssssns sssshsssaa
      181 ssstsssges eseegcssst easssastss psdvrrrrna aangkkkqkp lsaaavaaas
      241 tcssslaalk kstkssssas asttsvggkq ykdpsmkqli gklndlwpeh svalsipkev
      301 dkskeklega wettgrdgsk ittvvatpgq gtdrvqevsy tdtkvigngs fgvvfqaklc
      361 dtgelvaikk vlqdrrfknr elqimrkleh cnivkllyff yssgekrdev flnlvleyip
      421 etvykvarqy aktkqtipin firlymyqlf rslayihslg ichrdikpqn llldpetavl
      481 klcdfgsakq llhgepnvsy icsryyrape lifgainytt kidvwsagcv laelllgqpi
      541 fpgdsgvdql vevikvlgtp treqiremnp nytefkfpqi kshpwqkvfr irtpteainl
      601 vsllleytps aritplkaca hpffdelrme gnhtlpngrd mpplfnftdh elsiqpslvp
      661 qllpkhlatr ssgggpaaag avsgstsvss tgsgasadga aqaqvggtag ssaagsgsgs
      721 gaaaaaaaag gpatgsnagg qgnnsnpgsg apsavaaapa aqqanaggaa aagggggggg
      781 aagaataags vaatnaggan vtgsqsnsal nssstangng sgngeaaagg gasgsaaggd
      841 engataaaaa gaeteaeaaa vsg