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putative GTPase [Candida albicans SC5314].


LOCUS       XP_019331013             533 aa            linear   PLN 18-APR-2022
ACCESSION   XP_019331013
VERSION     XP_019331013.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_019475468.1
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 533)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 533)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 533)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 533)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 533)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 533)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30293.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..533
                     /product="putative GTPase"
                     /calculated_mol_wt=61081
     Region          41..171
                     /region_name="NGP1NT"
                     /note="NGP1NT (NUC091) domain; pfam08153"
                     /db_xref="CDD:462379"
     Region          214..370
                     /region_name="NGP_1"
                     /note="A novel nucleolar GTP-binding protein, circularly
                     permuted subfamily of the Ras GTPases; cd01858"
                     /db_xref="CDD:206751"
     Site            order(260..261,263..264,289..291,324..330,369)
                     /site_type="other"
                     /note="GTP/Mg2+ binding site [chemical binding]"
                     /db_xref="CDD:206751"
     Site            260..263
                     /site_type="other"
                     /note="G4 box"
                     /db_xref="CDD:206751"
     Site            289..291
                     /site_type="other"
                     /note="G5 box"
                     /db_xref="CDD:206751"
     Region          319..>431
                     /region_name="P-loop containing Nucleoside Triphosphate
                     Hydrolases"
                     /note="Members of the P-loop NTPase domain superfamily are
                     characterized by a conserved nucleotide phosphate-binding
                     motif, also referred to as the Walker A motif
                     (GxxxxGK[S/T], where x is any residue), and the Walker B
                     motif (hhhh[D/E], where h is a...; cl38936"
                     /db_xref="CDD:476819"
     Site            322..329
                     /site_type="other"
                     /note="G1 box"
                     /db_xref="CDD:206751"
     Site            322..329
                     /site_type="other"
                     /note="G1 box"
                     /db_xref="CDD:206668"
     Site            347..354
                     /site_type="other"
                     /note="Switch I region"
                     /db_xref="CDD:206751"
     Site            350
                     /site_type="other"
                     /note="G2 box"
                     /db_xref="CDD:206751"
     Site            350
                     /site_type="other"
                     /note="G2 box"
                     /db_xref="CDD:206668"
     Site            366..369
                     /site_type="other"
                     /note="G3 box"
                     /db_xref="CDD:206751"
     Site            366..369
                     /site_type="other"
                     /note="G3 box"
                     /db_xref="CDD:206668"
     Site            order(368..369,395..396)
                     /site_type="other"
                     /note="Switch II region"
                     /db_xref="CDD:206668"
     Site            368..370
                     /site_type="other"
                     /note="Switch II region"
                     /db_xref="CDD:206751"
     CDS             1..533
                     /gene="NOG2"
                     /locus_tag="CAALFM_C603640WA"
                     /coded_by="XM_019475468.1:1..1602"
                     /note="Putative nucleolar GTPase; repressed by
                     prostaglandins; Hap43-induced, rat catheter and Spider
                     biofilm induced"
                     /transl_table=12
                     /db_xref="CGD:CAL0000182741"
                     /db_xref="GeneID:3640299"
ORIGIN      
        1 mgtqkkekqr rvrendtrdg nlrvkgenfy rdakkvkhln mykqgrairn kkgeiikaad
       61 lqstdipnar vdpnrkwfgn trviaqdalt hfrevmgeks kdsyqvllkr nklpmsllde
      121 kdttesptak ivetesysst fgpkqqrkkp rvaassledl mnaaeadstq fqekqeldst
      181 lglmggsild kddftqeake aifhkgqskr iwnelykvid ssdvvihvld ardpvgtrce
      241 svekyikdec phkhliyvln kcdlvptwva aawvkhlsks fptlafhasi tnsfgkgsli
      301 qllrqfstlh sdrkqisvgf igypntgkss iintlrkkkv cqvapipget kvwqyitlmk
      361 riflidcpgi vppsskdtes dilfrgvvrv ehvsnpeqyi pdmlqkcerk hlertyeikg
      421 wskfeedesl lerastefie liarkqgrll kggepdesgv skqilndfnr gkipwfvppp
      481 kdeekdedkt gedkkigykr krqereaaek elqekeenqd eddkevkkak lee