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Fpg1p [Candida albicans SC5314].


LOCUS       XP_019331003             372 aa            linear   PLN 18-APR-2022
ACCESSION   XP_019331003
VERSION     XP_019331003.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_019475458.1
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 372)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 372)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 372)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 372)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 372)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 372)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30118.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..372
                     /product="Fpg1p"
                     /calculated_mol_wt=42678
     Region          1..171
                     /region_name="PF_Nei_N"
                     /note="N-terminal domain of the plant and fungal Nei and
                     related proteins; cd08972"
                     /db_xref="CDD:176806"
     Region          2..355
                     /region_name="Nei"
                     /note="Formamidopyrimidine-DNA glycosylase [Replication,
                     recombination and repair]; COG0266"
                     /db_xref="CDD:440036"
     Site            order(2..3,68,86,88..90,140..141)
                     /site_type="other"
                     /note="putative DNA binding site [nucleotide binding]"
                     /db_xref="CDD:176806"
     Site            2
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:176806"
     Site            order(3..6,8..9,12,65..69)
                     /site_type="other"
                     /note="putative H2TH interface [polypeptide binding]"
                     /db_xref="CDD:176806"
     Site            order(3,68)
                     /site_type="active"
                     /note="putative catalytic residues [active]"
                     /db_xref="CDD:176806"
     CDS             1..372
                     /gene="FPG1"
                     /locus_tag="CAALFM_C601820CA"
                     /coded_by="XM_019475458.1:1..1119"
                     /note="Formamidopyrimidine DNA glycosylase, involved in
                     repair of gamma-irradiated DNA; Hap43p-repressed gene"
                     /transl_table=12
                     /db_xref="CGD:CAL0000181241"
                     /db_xref="GeneID:3641632"
ORIGIN      
        1 mpevaevshv callkrnilg fritkvnllh dpllfpvlkn tndaekelnk mrkvltnavv
       61 tsvgrhgkyf wirlnnhntt nvllmhfgmt gmiklrnvhs hlafmenggd kkaleklerf
      121 rykdsrikpd vevkqewppr ftkfnmelen ndkklefafs dprrlarvrl lsglevstde
      181 sllklsplna lgpdyskpev ppkesepfvf gdpdsdnhgr arlsidefsa lilskkkpik
      241 sllldqtyfa gvgnwvadev lfqahihpne ilsskiskdl eyvhpviqql ydsliyvcee
      301 avrvegdvak fpddwlmlhr wgkgrkekrk tpngyildhi tvggrtscyc pelqrlikve
      361 tatttkrrkv kr