Zcf18p [Candida albicans SC5314].

LOCUS       XP_019331002             510 aa            linear   PLN 18-APR-2022
ACCESSION   XP_019331002
VERSION     XP_019331002.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_019475457.1
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 510)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 510)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 510)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 510)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 510)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 510)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30116.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..510
                     /product="Zcf18p"
                     /calculated_mol_wt=59097
     Region          12..47
                     /region_name="GAL4"
                     /note="GAL4-like Zn2Cys6 binuclear cluster DNA-binding
                     domain; found in transcription regulators like GAL4.
                     Domain consists of two helices organized around a
                     Zn(2)Cys(6)motif; Binds to sequences containing 2 DNA half
                     sites comprised of 3-5 C/G combinations; cd00067"
                     /db_xref="CDD:238023"
     Site            order(12,16,21..24,26,29,39)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238023"
     Site            order(17,20,27,34,37,44)
                     /site_type="other"
                     /note="Zn2+ binding site [ion binding]"
                     /db_xref="CDD:238023"
     CDS             1..510
                     /gene="ZCF18"
                     /locus_tag="CAALFM_C601790CA"
                     /coded_by="XM_019475457.1:1..1533"
                     /note="Putative Zn(II)2Cys6 transcription factor;
                     heterozygous null mutant displays sensitivity to
                     virgineone and decreased colonization of mouse kidneys"
                     /transl_table=12
                     /db_xref="CGD:CAL0000179911"
                     /db_xref="GeneID:3641635"
ORIGIN      
        1 msvpltkekk krsrggcvsc kklkikcneq kpiceycryt krtciypila pikgyrrkts
       61 rspqeskdek tstphsstta ispissssts dklnnlyvsn nevpdinpyh ydklsrdlvl
      121 tnstsmlgit rfelrllqff dqecinffsf gvnknihntw kykvpylfle selvrksmfa
      181 lsamglsttl dldelqsida dedekslvni yntnvdeldn ifenttkyfm dtisktkhmi
      241 gsieddsnia sfddpksake llvssilvfs ylgvhphrls plidftqerg dliqiskgir
      301 ytimscapti lksdmspllf fhgiekmqtp tfekcqypii qdlkndidef gsgegsseis
      361 eelsilkdvv arlmmcingc kffkfpiplf rflmlfddhf rdllynkhrl alrilyvysa
      421 lcsicrfqff dernvwkdym twyrgyaaen fdgyknetde ylyflaaieh fhwddftnfd
      481 kfnpkaefek viqsgkyrkq sllvgqnsnc