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cdc42 homolog [Drosophila takahashii].


LOCUS       XP_017016075             191 aa            linear   INV 09-DEC-2024
ACCESSION   XP_017016075
VERSION     XP_017016075.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017160586.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..191
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..191
                     /product="cdc42 homolog"
                     /calculated_mol_wt=21259
     Region          3..177
                     /region_name="Cdc42"
                     /note="cell division cycle 42 (Cdc42) is a small GTPase of
                     the Rho family; cd01874"
                     /db_xref="CDD:206664"
     Site            order(3,5,31..32,35..36,38..39,41,43,52,56..61,64..67,
                     70..71,73..74,103..104)
                     /site_type="other"
                     /note="GEF (guanine nucleotide exchange factor)
                     interaction site [polypeptide binding]"
                     /db_xref="CDD:206664"
     Site            order(4,7..13,16,20..21,23,28,30..48,52..53,57..63,67..68,
                     70,116,120,166,170,173..174,177)
                     /site_type="active"
                     /note="ACK tyrosine kinase interaction site [active]"
                     /db_xref="CDD:206664"
     Site            10..17
                     /site_type="other"
                     /note="G1 box"
                     /db_xref="CDD:206664"
     Site            order(13..18,29,32..33,35,57..58,60,116,118,159..160)
                     /site_type="other"
                     /note="GTP/Mg2+ binding site [chemical binding]"
                     /db_xref="CDD:206664"
     Site            order(20..21,36,38,40,46,67,70,173..174,177)
                     /site_type="active"
                     /note="CRIB effector interaction site [active]"
                     /db_xref="CDD:206664"
     Site            order(23..25,37,39..41,43,45..47,64,166)
                     /site_type="active"
                     /note="Par6 cell polarity protein interaction site
                     [active]"
                     /db_xref="CDD:206664"
     Site            25..40
                     /site_type="other"
                     /note="Switch I region"
                     /db_xref="CDD:206664"
     Site            order(32,34,36..37,61..64,67,70)
                     /site_type="other"
                     /note="GAP (GTPase-activating protein) interaction site
                     [polypeptide binding]"
                     /db_xref="CDD:206664"
     Site            order(35..36,59,64,66..67,69..70,73,103..104,106)
                     /site_type="other"
                     /note="GDI (guanine nucleotide dissociation inhibitor)
                     interaction site [polypeptide binding]"
                     /db_xref="CDD:206664"
     Site            35
                     /site_type="other"
                     /note="G2 box"
                     /db_xref="CDD:206664"
     Site            57..60
                     /site_type="other"
                     /note="G3 box"
                     /db_xref="CDD:206664"
     Site            59..77
                     /site_type="other"
                     /note="Switch II region"
                     /db_xref="CDD:206664"
     Site            115..118
                     /site_type="other"
                     /note="G4 box"
                     /db_xref="CDD:206664"
     Site            158..160
                     /site_type="other"
                     /note="G5 box"
                     /db_xref="CDD:206664"
     CDS             1..191
                     /gene="Cdc42"
                     /coded_by="XM_017160586.3:168..743"
                     /db_xref="GeneID:108070204"
ORIGIN      
        1 mqtikcvvvg dgavgktcll isyttnkfps eyvptvfdny avtvmiggep ytlglfdtag
       61 qedydrlrpl sypqtdvflv cfsvvspssf envkekwvpe ithhcqktpf llvgtqidlr
      121 detstlekla knkqkpitme qgeklakelk avkyvecsal tqkglknvfd eailaalepp
      181 eptkkrkckf l