histone deacetylase 4 isoform X4 [Drosophila takahashii].

LOCUS       XP_017015199            1228 aa            linear   INV 09-DEC-2024
ACCESSION   XP_017015199
VERSION     XP_017015199.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017159710.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017015199.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1228
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1228
                     /product="histone deacetylase 4 isoform X4"
                     /calculated_mol_wt=131204
     Region          43..>97
                     /region_name="ClassIIa_HDAC_Gln-rich-N"
                     /note="Glutamine-rich N-terminal helical domain of various
                     Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9);
                     cl25407"
                     /db_xref="CDD:421006"
     Site            order(47,51,55,58,62,65,69..70,73..74,77,81)
                     /site_type="other"
                     /note="dimer interface A, D [polypeptide binding]"
                     /db_xref="CDD:188886"
     Region          <480..>510
                     /region_name="CDF_efflux_DmeF"
                     /note="CDF family Co(II)/Ni(II) efflux transporter DmeF;
                     NF033827"
                     /db_xref="CDD:468196"
     Region          799..1173
                     /region_name="HDAC_classIIa"
                     /note="Histone deacetylases, class IIa; cd11681"
                     /db_xref="CDD:212544"
     Site            order(946..947,955..956,985,987,1079,1119)
                     /site_type="active"
                     /db_xref="CDD:212544"
     CDS             1..1228
                     /gene="HDAC4"
                     /coded_by="XM_017159710.3:725..4411"
                     /db_xref="GeneID:108069580"
ORIGIN      
        1 msspddripi hdlpseagsd erllhitpgt ltldfkphpa vdidqqimel kksqelqkqr
       61 lfhtfqeqsk qmelehklql ehkyqfavns hgafqelrte smvtaaaaaa avaeeqhrqq
      121 qqqqhqhqqh qqhqqqqqqh qqqqqhqqqq qqqqgrgrdg mklnktcsan aspevkqiln
      181 cfimsrksqa aqsngtttsp yrnrgvvkss sgeslpagtv tsahpykipq ppssllkyes
      241 dfplrktdcn stpdsgpnsp psaaalsvgv vgsrgsptsa piqeeneegs qyqpgqrssi
      301 ndlplfssps lpnislgrph lpnsahsqha qvaaqaqaqv aaqaaqaaqa qahamfaalh
      361 qhvaaaggqp ggyynplsma afvgrqpapm smipatgiap qqpspvvrsa satstsssqa
      421 slvgdvappq ahaastilps sssymqqmgs gvnihaisav aaaaaaaaaa agslpptnsh
      481 gaqhghsnhh glahghgpha lygghghqhn vpitdaqvaq vhlhkqghrp lgrtqsaplp
      541 lghpmltgaa qlnvvqthye nseaerqaye hqvlnqklrq tvltrsgaaa aaaaaagvgv
      601 svgvvreaql keedddsaae vmdltdkkkp pktvltstia tstsqnlpea laaavaaaay
      661 rgappstsss aaaattaank iagggiklrd qeylqqqreq llllqqeeel akglmrplsr
      721 tlssplvplg phglsqipdt gqqpapiats ssadhippvn lslphrqhrq lmstlyasql
      781 rnhqqlhqpp ssgspphkvt tglaydplml khscicgdna qhpehsgrlq svwarlnetd
      841 lvkrcdrlra rkatqeelqt vhteahamlf gsnqcqlsrp klentlsasf vrlscgglgv
      901 dldttwnehh tataarmaag cvidlalkta kgdlrngfav vrppghhaea nlamgfcffn
      961 siaiaakllr qrmpevrril ivdwdvhhgn gtqqafyqsp dilylsihrh ddgnffpgtg
     1021 gptecgsgag lgfnvnisws galnpplgda eyiaafrtvv mpiarsfnpd ivlvssgfda
     1081 atghpaplgg yhvspacfgf mtrellqlan gkvvlalegg ydlaaicdsa qecvrallgd
     1141 paapiaqael erppcqnain tlqktiaiqq thwpcvrmle htvglsalet lkvehdeset
     1201 inamaglsmh rtlsrddsee pmdqdetk