histone deacetylase 4 isoform X3 [Drosophila takahashii].

LOCUS       XP_017015198            1230 aa            linear   INV 09-DEC-2024
ACCESSION   XP_017015198
VERSION     XP_017015198.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017159709.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017015198.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1230
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1230
                     /product="histone deacetylase 4 isoform X3"
                     /calculated_mol_wt=131586
     Region          3..>50
                     /region_name="ClassIIa_HDAC_Gln-rich-N"
                     /note="Glutamine-rich N-terminal helical domain of various
                     Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9);
                     cl25407"
                     /db_xref="CDD:421006"
     Site            order(4,8,11,15,18,22..23,26..27,30,34)
                     /site_type="other"
                     /note="dimer interface A, D [polypeptide binding]"
                     /db_xref="CDD:188886"
     Region          <482..>512
                     /region_name="CDF_efflux_DmeF"
                     /note="CDF family Co(II)/Ni(II) efflux transporter DmeF;
                     NF033827"
                     /db_xref="CDD:468196"
     Region          801..1175
                     /region_name="HDAC_classIIa"
                     /note="Histone deacetylases, class IIa; cd11681"
                     /db_xref="CDD:212544"
     Site            order(948..949,957..958,987,989,1081,1121)
                     /site_type="active"
                     /db_xref="CDD:212544"
     CDS             1..1230
                     /gene="HDAC4"
                     /coded_by="XM_017159709.3:803..4495"
                     /db_xref="GeneID:108069580"
ORIGIN      
        1 melkksqelq kqrlfhtfqe qskqmelehk lqlehkyqfa vnshgafqel rtesmvtaaa
       61 aaaavaeeqh rqqqqqqhqh qqhqqhqqqq qqhqqqqqhq qqqqqqqgrg rdgmklnktc
      121 sanaspevkq ilncfimsrk sqaaqsngtt tspyrnrgvv ksssgeslpa gtvtsahpyk
      181 ipqppssllk yesdfplrkt asepnllkir lkqsvierka riggpvgarr herllqaaqr
      241 rqqknsvltn cnstpdsgpn sppsaaalsv gvvgsrgspt sapiqeenee gsqyqpgqrs
      301 sindlplfss pslpnislgr phlpnsahsq haqvaaqaqa qvaaqaaqaa qaqahamfaa
      361 lhqhvaaagg qpggyynpls maafvgrqpa pmsmipatgi apqqpspvvr sasatstsss
      421 qaslvgdvap pqahaastil pssssymqqm gsgvnihais avaaaaaaaa aaagslpptn
      481 shgaqhghsn hhglahghgp halygghghq hnvpitdaqv aqvhlhkqgh rplgrtqsap
      541 lplghpmltg aaqlnvvqth yenseaerqa yehqvlnqkl rqtvltrsga aaaaaaaagv
      601 gvsvgvvrea qlkeedddsa aevmdltdkk kppktvltst iatstsqnlp ealaaavaaa
      661 ayrgappsts ssaaaattaa nkiagggikl rdqeylqqqr eqllllqqee elakglmrpl
      721 srtlssplvp lgphglsqip dtgqqpapia tsssadhipp vnlslphrqh rqlmstlyas
      781 qlrnhqqlhq ppssgspphk vttglaydpl mlkhscicgd naqhpehsgr lqsvwarlne
      841 tdlvkrcdrl rarkatqeel qtvhteaham lfgsnqcqls rpklentlsa sfvrlscggl
      901 gvdldttwne hhtataarma agcvidlalk takgdlrngf avvrppghha eanlamgfcf
      961 fnsiaiaakl lrqrmpevrr ilivdwdvhh gngtqqafyq spdilylsih rhddgnffpg
     1021 tggptecgsg aglgfnvnis wsgalnpplg daeyiaafrt vvmpiarsfn pdivlvssgf
     1081 daatghpapl ggyhvspacf gfmtrellql angkvvlale ggydlaaicd saqecvrall
     1141 gdpaapiaqa elerppcqna intlqktiai qqthwpcvrm lehtvglsal etlkvehdes
     1201 etinamagls mhrtlsrdds eepmdqdetk