histone deacetylase 4 isoform X2 [Drosophila takahashii].

LOCUS       XP_017015197            1267 aa            linear   INV 09-DEC-2024
ACCESSION   XP_017015197
VERSION     XP_017015197.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017159708.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017015197.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1267
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1267
                     /product="histone deacetylase 4 isoform X2"
                     /calculated_mol_wt=135699
     Region          43..>81
                     /region_name="ClassIIa_HDAC_Gln-rich-N"
                     /note="Glutamine-rich N-terminal helical domain of various
                     Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9);
                     cl25407"
                     /db_xref="CDD:421006"
     Site            order(47,51,55,58,62,65,69..70,73..74,77,81)
                     /site_type="other"
                     /note="dimer interface A, D [polypeptide binding]"
                     /db_xref="CDD:188886"
     Region          <519..>549
                     /region_name="CDF_efflux_DmeF"
                     /note="CDF family Co(II)/Ni(II) efflux transporter DmeF;
                     NF033827"
                     /db_xref="CDD:468196"
     Region          838..1212
                     /region_name="HDAC_classIIa"
                     /note="Histone deacetylases, class IIa; cd11681"
                     /db_xref="CDD:212544"
     Site            order(985..986,994..995,1024,1026,1118,1158)
                     /site_type="active"
                     /db_xref="CDD:212544"
     CDS             1..1267
                     /gene="HDAC4"
                     /coded_by="XM_017159708.3:726..4529"
                     /db_xref="GeneID:108069580"
ORIGIN      
        1 msspddripi hdlpseagsd erllhitpgt ltldfkphpa vdidqqimel kksqelqkqr
       61 lfhtfqeqsk qmelehklql ehkyqelrte smvtaaaaaa avaeeqhrqq qqqqhqhqqh
      121 qqhqqqqqqh qqqqqhqqqq qqqqgrgrdg mklnktcsan aspevkqiln cfimsrksqa
      181 aqsngtttsp yrnrgvvkss sgeslpagtv tsahpykipq ppssllkyes dfplrktase
      241 pnllkirlkq svierkarig gpvgarrher llqaaqrrqq knsvltncns tpdsgpnspp
      301 saaalsvgvv gsrgsptsap iqeeneegsq yqpgqrssin dlplfsspsl pnislgrphl
      361 pnsahsqhaq vaaqaqaqva aqaaqaaqaq ahamfaalhq hvaaaggqpg gyynplsmaa
      421 fvgrqpapms mipatgiapq qpspvvrsas atstsssqas lvgdvappqa haastilpss
      481 ssymqqmgsg vnihaisava aaaaaaaaaa gslpptnshg aqhghsnhhg lahghgphal
      541 ygghghqhnv pitdaqvaqv hlhkqghrpl grtqsaplpl ghpmltgaaq lnvvqthyen
      601 seaerqayeh qvlnqklrqt vltrsgaaaa aaaaagvgvs vgvvreaqlk eedddsaaev
      661 mdltdkkkpp ktvltstiat stsqnlpeal aaavaaaayr gappstsssa aaattaanki
      721 agggiklrdq eylqqqreql lllqqeeela kglmrplsrt lssplvplgp hglsqipdtg
      781 qqpapiatss sadhippvnl slphrqhrql mstlyasqlr nhqqlhqpps sgspphkvtt
      841 glaydplmlk hscicgdnaq hpehsgrlqs vwarlnetdl vkrcdrlrar katqeelqtv
      901 hteahamlfg snqcqlsrpk lentlsasfv rlscgglgvd ldttwnehht ataarmaagc
      961 vidlalktak gdlrngfavv rppghhaean lamgfcffns iaiaakllrq rmpevrrili
     1021 vdwdvhhgng tqqafyqspd ilylsihrhd dgnffpgtgg ptecgsgagl gfnvniswsg
     1081 alnpplgdae yiaafrtvvm piarsfnpdi vlvssgfdaa tghpaplggy hvspacfgfm
     1141 trellqlang kvvlaleggy dlaaicdsaq ecvrallgdp aapiaqaele rppcqnaint
     1201 lqktiaiqqt hwpcvrmleh tvglsaletl kvehdeseti namaglsmhr tlsrddseep
     1261 mdqdetk