histone deacetylase 4 isoform X1 [Drosophila takahashii].

LOCUS       XP_017015195            1277 aa            linear   INV 09-DEC-2024
ACCESSION   XP_017015195
VERSION     XP_017015195.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017159706.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017015195.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1277
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1277
                     /product="histone deacetylase 4 isoform X1"
                     /calculated_mol_wt=136758
     Region          43..>97
                     /region_name="ClassIIa_HDAC_Gln-rich-N"
                     /note="Glutamine-rich N-terminal helical domain of various
                     Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9);
                     cl25407"
                     /db_xref="CDD:421006"
     Site            order(47,51,55,58,62,65,69..70,73..74,77,81)
                     /site_type="other"
                     /note="dimer interface A, D [polypeptide binding]"
                     /db_xref="CDD:188886"
     Region          <529..>559
                     /region_name="CDF_efflux_DmeF"
                     /note="CDF family Co(II)/Ni(II) efflux transporter DmeF;
                     NF033827"
                     /db_xref="CDD:468196"
     Region          848..1222
                     /region_name="HDAC_classIIa"
                     /note="Histone deacetylases, class IIa; cd11681"
                     /db_xref="CDD:212544"
     Site            order(995..996,1004..1005,1034,1036,1128,1168)
                     /site_type="active"
                     /db_xref="CDD:212544"
     CDS             1..1277
                     /gene="HDAC4"
                     /coded_by="XM_017159706.3:725..4558"
                     /db_xref="GeneID:108069580"
ORIGIN      
        1 msspddripi hdlpseagsd erllhitpgt ltldfkphpa vdidqqimel kksqelqkqr
       61 lfhtfqeqsk qmelehklql ehkyqfavns hgafqelrte smvtaaaaaa avaeeqhrqq
      121 qqqqhqhqqh qqhqqqqqqh qqqqqhqqqq qqqqgrgrdg mklnktcsan aspevkqiln
      181 cfimsrksqa aqsngtttsp yrnrgvvkss sgeslpagtv tsahpykipq ppssllkyes
      241 dfplrktase pnllkirlkq svierkarig gpvgarrher llqaaqrrqq knsvltncns
      301 tpdsgpnspp saaalsvgvv gsrgsptsap iqeeneegsq yqpgqrssin dlplfsspsl
      361 pnislgrphl pnsahsqhaq vaaqaqaqva aqaaqaaqaq ahamfaalhq hvaaaggqpg
      421 gyynplsmaa fvgrqpapms mipatgiapq qpspvvrsas atstsssqas lvgdvappqa
      481 haastilpss ssymqqmgsg vnihaisava aaaaaaaaaa gslpptnshg aqhghsnhhg
      541 lahghgphal ygghghqhnv pitdaqvaqv hlhkqghrpl grtqsaplpl ghpmltgaaq
      601 lnvvqthyen seaerqayeh qvlnqklrqt vltrsgaaaa aaaaagvgvs vgvvreaqlk
      661 eedddsaaev mdltdkkkpp ktvltstiat stsqnlpeal aaavaaaayr gappstsssa
      721 aaattaanki agggiklrdq eylqqqreql lllqqeeela kglmrplsrt lssplvplgp
      781 hglsqipdtg qqpapiatss sadhippvnl slphrqhrql mstlyasqlr nhqqlhqpps
      841 sgspphkvtt glaydplmlk hscicgdnaq hpehsgrlqs vwarlnetdl vkrcdrlrar
      901 katqeelqtv hteahamlfg snqcqlsrpk lentlsasfv rlscgglgvd ldttwnehht
      961 ataarmaagc vidlalktak gdlrngfavv rppghhaean lamgfcffns iaiaakllrq
     1021 rmpevrrili vdwdvhhgng tqqafyqspd ilylsihrhd dgnffpgtgg ptecgsgagl
     1081 gfnvniswsg alnpplgdae yiaafrtvvm piarsfnpdi vlvssgfdaa tghpaplggy
     1141 hvspacfgfm trellqlang kvvlaleggy dlaaicdsaq ecvrallgdp aapiaqaele
     1201 rppcqnaint lqktiaiqqt hwpcvrmleh tvglsaletl kvehdeseti namaglsmhr
     1261 tlsrddseep mdqdetk