dual specificity mitogen-activated protein kinase kinase 6

LOCUS       XP_017013285             334 aa            linear   INV 09-DEC-2024
            [Drosophila takahashii].
ACCESSION   XP_017013285
VERSION     XP_017013285.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017157796.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..334
                     /product="dual specificity mitogen-activated protein
                     kinase kinase 6"
                     /calculated_mol_wt=38222
     Region          44..326
                     /region_name="PKc_MKK3_6"
                     /note="Catalytic domain of the dual-specificity Protein
                     Kinases, Mitogen-activated protein Kinase Kinases 3 and 6;
                     cd06617"
                     /db_xref="CDD:173729"
     Site            order(48,50,52..59,61,63,75..76,78..80,112,114..115,117,
                     119,124..128,135,176..177,179,189,194,197..200,325..326)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:173729"
     Site            order(52..56,60,73,75,106,122..125,127..128,131,172,
                     174..177,179,189..190,193,206..209,211,242,251)
                     /site_type="active"
                     /db_xref="CDD:173729"
     Site            order(52..56,58,60,73,75,106,122..125,127..128,130..131,
                     174,176..177,179,190)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:173729"
     Site            order(55..56,172,174..176,193,206..209,211,242,251)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:173729"
     Site            order(189..204,206..211)
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:173729"
     CDS             1..334
                     /gene="lic"
                     /coded_by="XM_017157796.3:370..1374"
                     /db_xref="GeneID:108068310"
ORIGIN      
        1 msrrprlspf siskepepai vpprnldsra tiqigeqtfd idadslekic dlgrgaygiv
       61 ekmrhrqtdt vlavkripmt vnireqhrlv mdldismrss dcpytvhfyg amyregdvwi
      121 cmevmstsld kfypkvfrhd lrmeesvlgk iamsvvsalh ylhaqlkvih rdvkpsnili
      181 nragqvkicd fgisgylvds iaktidagck pymaperidp qgnpaqydir sdvwslgism
      241 iematgrypy dnwrtpfeql rqvveddppr lpagtfspef edfiavslqk eymerpnyeq
      301 llkhsfiveh lqrntdisef varildlpdn qpaq