glutathione S-transferase theta-1 isoform X2 [Drosophila

LOCUS       XP_017012881             250 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_017012881
VERSION     XP_017012881.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017157392.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017012881.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..250
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..250
                     /product="glutathione S-transferase theta-1 isoform X2"
                     /calculated_mol_wt=29326
     Region          27..103
                     /region_name="GST_N_Theta"
                     /note="GST_N family, Class Theta subfamily; composed of
                     eukaryotic class Theta GSTs and bacterial dichloromethane
                     (DCM) dehalogenase. GSTs are cytosolic dimeric proteins
                     involved in cellular detoxification by catalyzing the
                     conjugation of glutathione (GSH) with...; cd03050"
                     /db_xref="CDD:239348"
     Site            order(33..34,36,39..40,42..44,47,61)
                     /site_type="other"
                     /note="C-terminal domain interface [polypeptide binding]"
                     /db_xref="CDD:239348"
     Site            order(35..36,64..65,78..79,91..92)
                     /site_type="other"
                     /note="GSH binding site (G-site) [chemical binding]"
                     /db_xref="CDD:239348"
     Site            36
                     /site_type="active"
                     /note="sulfate binding site [active]"
                     /db_xref="CDD:239348"
     Site            order(75,87..88,90..91,94)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:239348"
     Region          117..241
                     /region_name="GST_C_Theta"
                     /note="C-terminal, alpha helical domain of Class Theta
                     Glutathione S-transferases; cd03183"
                     /db_xref="CDD:198292"
     Site            order(118..119,122,125..126)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:198292"
     Site            order(128,132..133,136..137,139..140,144,198,201)
                     /site_type="other"
                     /note="substrate binding pocket (H-site) [chemical
                     binding]"
                     /db_xref="CDD:198292"
     Site            order(193,197..198,201,233..234,237..238)
                     /site_type="other"
                     /note="N-terminal domain interface [polypeptide binding]"
                     /db_xref="CDD:198292"
     CDS             1..250
                     /gene="GstT3"
                     /coded_by="XM_017157392.3:75..827"
                     /db_xref="GeneID:108068036"
ORIGIN      
        1 mfwpqspsdc fcvpfrqptn lkmsspiryy ydlmsqpsra lfiifrlsnm pfedcvvalr
       61 ngehltddfk qqinrfqrvp cihdngykla esvailryls akgkipehly pkyfvdqsrv
      121 deflewqhms lrltcamyfr tvwleplltg rtpseakiet frmhmernld vveevwlegk
      181 dfltgstlsv adifaaceie qtrmadydvr ikypkirawl krvrqscnph ydvahefvyk
      241 isgtgpqakl