glutathione S-transferase theta-1 isoform X1 [Drosophila

LOCUS       XP_017012880             268 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_017012880
VERSION     XP_017012880.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017157391.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017012880.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..268
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..268
                     /product="glutathione S-transferase theta-1 isoform X1"
                     /calculated_mol_wt=31239
     Region          45..121
                     /region_name="GST_N_Theta"
                     /note="GST_N family, Class Theta subfamily; composed of
                     eukaryotic class Theta GSTs and bacterial dichloromethane
                     (DCM) dehalogenase. GSTs are cytosolic dimeric proteins
                     involved in cellular detoxification by catalyzing the
                     conjugation of glutathione (GSH) with...; cd03050"
                     /db_xref="CDD:239348"
     Site            order(51..52,54,57..58,60..62,65,79)
                     /site_type="other"
                     /note="C-terminal domain interface [polypeptide binding]"
                     /db_xref="CDD:239348"
     Site            order(53..54,82..83,96..97,109..110)
                     /site_type="other"
                     /note="GSH binding site (G-site) [chemical binding]"
                     /db_xref="CDD:239348"
     Site            54
                     /site_type="active"
                     /note="sulfate binding site [active]"
                     /db_xref="CDD:239348"
     Site            order(93,105..106,108..109,112)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:239348"
     Region          135..259
                     /region_name="GST_C_Theta"
                     /note="C-terminal, alpha helical domain of Class Theta
                     Glutathione S-transferases; cd03183"
                     /db_xref="CDD:198292"
     Site            order(136..137,140,143..144)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:198292"
     Site            order(146,150..151,154..155,157..158,162,216,219)
                     /site_type="other"
                     /note="substrate binding pocket (H-site) [chemical
                     binding]"
                     /db_xref="CDD:198292"
     Site            order(211,215..216,219,251..252,255..256)
                     /site_type="other"
                     /note="N-terminal domain interface [polypeptide binding]"
                     /db_xref="CDD:198292"
     CDS             1..268
                     /gene="GstT3"
                     /coded_by="XM_017157391.3:92..898"
                     /db_xref="GeneID:108068036"
ORIGIN      
        1 msvsflatll glsndedqlr laleevenpr vpfrqptnlk msspiryyyd lmsqpsralf
       61 iifrlsnmpf edcvvalrng ehltddfkqq inrfqrvpci hdngyklaes vailrylsak
      121 gkipehlypk yfvdqsrvde flewqhmslr ltcamyfrtv wleplltgrt pseakietfr
      181 mhmernldvv eevwlegkdf ltgstlsvad ifaaceieqt rmadydvrik ypkirawlkr
      241 vrqscnphyd vahefvykis gtgpqakl