disks large 1 tumor suppressor protein isoform X23 [Drosophila

LOCUS       XP_017011159             914 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_017011159
VERSION     XP_017011159.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017155670.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017011159.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..914
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..914
                     /product="disks large 1 tumor suppressor protein isoform
                     X23"
                     /calculated_mol_wt=100913
     Region          158..246
                     /region_name="PDZ1_Dlg1-2-4-like"
                     /note="PDZ domain 1 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06723"
                     /db_xref="CDD:467206"
     Site            order(169..175,192,195,225,229,232..233)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467206"
     Region          272..360
                     /region_name="PDZ2_Dlg1-2-4-like"
                     /note="PDZ domain 2 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06724"
                     /db_xref="CDD:467207"
     Site            order(281..287,304,307,341,345,348..349)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467207"
     Region          447..537
                     /region_name="PDZ3_Dlg1-2-4-like"
                     /note="PDZ domain 3 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06795"
                     /db_xref="CDD:467257"
     Site            order(459..465,476,479,509,513,516..517)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467257"
     Region          568..628
                     /region_name="SH3_DLG-like"
                     /note="Src Homology 3 domain of Disks large homolog
                     proteins; cd11861"
                     /db_xref="CDD:212795"
     Site            order(570,592..593)
                     /site_type="other"
                     /note="GuK domain interface [polypeptide binding]"
                     /db_xref="CDD:212795"
     Site            order(573,575,578,587,605..606,625,627..628)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212795"
     Region          723..901
                     /region_name="Guanylate_kin"
                     /note="Guanylate kinase; pfam00625"
                     /db_xref="CDD:395500"
     CDS             1..914
                     /gene="dlg1"
                     /coded_by="XM_017155670.3:16..2760"
                     /db_xref="GeneID:108066907"
ORIGIN      
        1 midwvsivrh srrrfsnyvg srspvrmrrr rrqltapppp qqqqqqqqqh qqeqhqsrdr
       61 qkkdkeiere kerdkdsdsg ggsryaccca nnqrmriesd tenakeppae qqqqrssrsp
      121 qqnpqqqqpq qqqqpqqqlg sksrsgsqtv ngddswlyed iqlergnsgl gfsiaggtdn
      181 phigtdtsiy itklisggaa aadgrlsind iivsvnevsv vdvphasavd alkkagnvvk
      241 lhvkrkrdta attpaagsaa gdardggpkv meidlvkggk glgfsiaggi gnqhipgdng
      301 iyvtklmdgg aaqvdgrlni gdkliavrtn gseknlenvt helavatlks itdkvtliig
      361 ktqhlttsas gggggglssg qqlsqsqsql atsqsqsqvh qqqqqhqtpm vnsqstepgs
      421 ryastnvlaa vppgtpravs teditreprt itiqkgpqgl gfnivggedg qgiyvsfila
      481 ggpadlgsel krgdqllsvn nvnlthathe eaaqalktsg gvvtllaqyr peeynrfear
      541 iqelkqqaal gaggsgtllr ttqkrslyvr alfdydpnrd dglpsrglpf khgdilhvtn
      601 asddewwqar rvlgdnedeq igivpskrrw erkmrardrs vkfqghaaan nnvdkqstld
      661 rkkknftfsr kfpfmksrde knedgsdqep fmlcytqdda naegaseenv lsyeavqrls
      721 inytrpviil gplkdrindd liseypdkfg scvphttrpk reyevdgrdy hfvssreqme
      781 rdiqnhlfie agqyndnlyg tsvasvreva ekgkhcildv sgnaikrlqv aqlypvavfi
      841 kpksvdsvme mnrrmteeqa kktyeraikm eqefgeyftg vvqgdtieei yskvksmiws
      901 qsgptiwvps kesl