disks large 1 tumor suppressor protein isoform X22 [Drosophila

LOCUS       XP_017011158             915 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_017011158
VERSION     XP_017011158.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017155669.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017011158.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..915
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..915
                     /product="disks large 1 tumor suppressor protein isoform
                     X22"
                     /calculated_mol_wt=100729
     Region          6..64
                     /region_name="L27_1"
                     /note="pfam09058"
                     /db_xref="CDD:462665"
     Region          159..247
                     /region_name="PDZ1_Dlg1-2-4-like"
                     /note="PDZ domain 1 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06723"
                     /db_xref="CDD:467206"
     Site            order(170..176,193,196,226,230,233..234)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467206"
     Region          273..361
                     /region_name="PDZ2_Dlg1-2-4-like"
                     /note="PDZ domain 2 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06724"
                     /db_xref="CDD:467207"
     Site            order(282..288,305,308,342,346,349..350)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467207"
     Region          448..538
                     /region_name="PDZ3_Dlg1-2-4-like"
                     /note="PDZ domain 3 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06795"
                     /db_xref="CDD:467257"
     Site            order(460..466,477,480,510,514,517..518)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467257"
     Region          569..629
                     /region_name="SH3_DLG-like"
                     /note="Src Homology 3 domain of Disks large homolog
                     proteins; cd11861"
                     /db_xref="CDD:212795"
     Site            order(571,593..594)
                     /site_type="other"
                     /note="GuK domain interface [polypeptide binding]"
                     /db_xref="CDD:212795"
     Site            order(574,576,579,588,606..607,626,628..629)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212795"
     Region          724..902
                     /region_name="Guanylate_kin"
                     /note="Guanylate kinase; pfam00625"
                     /db_xref="CDD:395500"
     CDS             1..915
                     /gene="dlg1"
                     /coded_by="XM_017155669.3:654..3401"
                     /db_xref="GeneID:108066907"
ORIGIN      
        1 mpvkkqeahr alelledyha rlsepqdral riaierviri fksrlfqall diqefyeltl
       61 lddsksiqqk taetlqiatk wekdgqavki adnqrmries dtenakeppa eqqqqrssrs
      121 pqqnpqqqqp qqqqqpqqql gsksrsgsqt vngddswlye diqlergnsg lgfsiaggtd
      181 nphigtdtsi yitklisgga aaadgrlsin diivsvnevs vvdvphasav dalkkagnvv
      241 klhvkrkrdt aattpaagsa agdardggpk vmeidlvkgg kglgfsiagg ignqhipgdn
      301 giyvtklmdg gaaqvdgrln igdkliavrt ngseknlenv thelavatlk sitdkvtlii
      361 gktqhlttsa sgggggglss gqqlsqsqsq latsqsqsqv hqqqqqhqtp mvnsqstepg
      421 sryastnvla avppgtprav steditrepr titiqkgpqg lgfnivgged gqgiyvsfil
      481 aggpadlgse lkrgdqllsv nnvnlthath eeaaqalkts ggvvtllaqy rpeeynrfea
      541 riqelkqqaa lgaggsgtll rttqkrslyv ralfdydpnr ddglpsrglp fkhgdilhvt
      601 nasddewwqa rrvlgdnede qigivpskrr werkmrardr svkfqghaaa nnnvdkqstl
      661 drkkknftfs rkfpfmksrd eknedgsdqe pfmlcytqdd anaegaseen vlsyeavqrl
      721 sinytrpvii lgplkdrind dliseypdkf gscvphttrp kreyevdgrd yhfvssreqm
      781 erdiqnhlfi eagqyndnly gtsvasvrev aekgkhcild vsgnaikrlq vaqlypvavf
      841 ikpksvdsvm emnrrmteeq akktyeraik meqefgeyft gvvqgdtiee iyskvksmiw
      901 sqsgptiwvp skesl