disks large 1 tumor suppressor protein isoform X12 [Drosophila

LOCUS       XP_017011144            1006 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_017011144
VERSION     XP_017011144.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017155655.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017011144.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1006
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1006
                     /product="disks large 1 tumor suppressor protein isoform
                     X12"
                     /calculated_mol_wt=109897
     Region          277..333
                     /region_name="L27_1"
                     /note="pfam09058"
                     /db_xref="CDD:462665"
     Region          428..516
                     /region_name="PDZ1_Dlg1-2-4-like"
                     /note="PDZ domain 1 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06723"
                     /db_xref="CDD:467206"
     Site            order(439..445,462,465,495,499,502..503)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467206"
     Region          542..630
                     /region_name="PDZ2_Dlg1-2-4-like"
                     /note="PDZ domain 2 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06724"
                     /db_xref="CDD:467207"
     Site            order(551..557,574,577,611,615,618..619)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467207"
     Region          717..807
                     /region_name="PDZ3_Dlg1-2-4-like"
                     /note="PDZ domain 3 of human discs large homolog 1 (Dlg1),
                     Dlg2, and Dlg4, Drosophila disc large (Dlg), and related
                     domains; cd06795"
                     /db_xref="CDD:467257"
     Site            order(729..735,746,749,779,783,786..787)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467257"
     Region          838..898
                     /region_name="SH3_DLG-like"
                     /note="Src Homology 3 domain of Disks large homolog
                     proteins; cd11861"
                     /db_xref="CDD:212795"
     Site            order(840,862..863)
                     /site_type="other"
                     /note="GuK domain interface [polypeptide binding]"
                     /db_xref="CDD:212795"
     Site            order(843,845,848,857,875..876,895,897..898)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212795"
     CDS             1..1006
                     /gene="dlg1"
                     /coded_by="XM_017155655.3:41..3061"
                     /db_xref="GeneID:108066907"
ORIGIN      
        1 mdsdtddser ekssdpnegl lssddktfhd ddeeedsspa ddeeepegee sllpqqqkka
       61 qplvvlvesg sgeaieepte eieidrvtlp ikeerepdpe pepsplkhds vresvecfys
      121 aqdlleyghm lsssggsivr tpdvesgyfe ksesdeggpp ssssslgaar crllsgisgl
      181 spvsssssrh saeglrmels rfrtmietle reslektkgk pkprqrsqlq vesagesgsd
      241 qgseremerg fwstvfgqag leisqdeder iadikkahra lelledyhar lsepqdralr
      301 iaiervirif ksrlfqalld iqefyeltll ddsksiqqkt aetlqiatkw ekdgqavkia
      361 dnqrmriesd tenakeppae qqqqrssrsp qqnpqqqqpq qqqqpqqqlg sksrsgsqtv
      421 ngddswlyed iqlergnsgl gfsiaggtdn phigtdtsiy itklisggaa aadgrlsind
      481 iivsvnevsv vdvphasavd alkkagnvvk lhvkrkrdta attpaagsaa gdardggpkv
      541 meidlvkggk glgfsiaggi gnqhipgdng iyvtklmdgg aaqvdgrlni gdkliavrtn
      601 gseknlenvt helavatlks itdkvtliig ktqhlttsas gggggglssg qqlsqsqsql
      661 atsqsqsqvh qqqqqhqtpm vnsqstepgs ryastnvlaa vppgtpravs teditreprt
      721 itiqkgpqgl gfnivggedg qgiyvsfila ggpadlgsel krgdqllsvn nvnlthathe
      781 eaaqalktsg gvvtllaqyr peeynrfear iqelkqqaal gaggsgtllr ttqkrslyvr
      841 alfdydpnrd dglpsrglpf khgdilhvtn asddewwqar rvlgdnedeq igivpskrrw
      901 erkmrardrs vkfqghaaan nnvdkqstld rkkknftfsr kfpfmksrde knedgsdqep
      961 fmlcytqdda naeggeiiyr velpdmeqit liylensdad yrkssi