bifunctional phosphoribosylaminoimidazole

LOCUS       XP_017011008             431 aa            linear   INV 09-DEC-2024
            carboxylase/phosphoribosylaminoimidazole succinocarboxamide
            synthetase [Drosophila takahashii].
ACCESSION   XP_017011008
VERSION     XP_017011008.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017155519.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..431
                     /product="bifunctional phosphoribosylaminoimidazole
                     carboxylase/phosphoribosylaminoimidazole
                     succinocarboxamide synthetase"
                     /calculated_mol_wt=47313
     Region          14..262
                     /region_name="SAICAR_synt_Ade5"
                     /note="Ade5_like
                     5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide
                     (SAICAR) synthase; cd01416"
                     /db_xref="CDD:133471"
     Site            order(20..21,23..24,26,28..29,38,40,83,96,98,100,138,200,
                     212..213)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:133471"
     Site            order(21,23..26,28,38,50,84,95..98,100,104,106,108,
                     112..114,136,138,144,196..198,200,213,218..221)
                     /site_type="active"
                     /db_xref="CDD:133471"
     Site            order(50,104,106,108,112..114,136,144,196..198,218..221)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:133471"
     Region          273..426
                     /region_name="purE"
                     /note="phosphoribosylaminoimidazole carboxylase, PurE
                     protein; TIGR01162"
                     /db_xref="CDD:273474"
     CDS             1..431
                     /gene="Paics"
                     /coded_by="XM_017155519.3:233..1528"
                     /db_xref="GeneID:108066828"
ORIGIN      
        1 mstaatttts iegyklgkvi iegktkqvyd lpeqpglcll lskdritagd gvkahdlagk
       61 aeisnttngq vfrllneagi rtayvkqcgs kafiarkcqm ipiewvtrrl atgsflkrnv
      121 gvpegyrfsp pkqetffkdd anhdpqwsee qivsakfeln glvigqdevd imrrttllvf
      181 eilerawqtk ncalidmkve fgicddgniv ladiidsdsw rlwpagdkrl mvdkqvyrnl
      241 asvtasdldt vkrnfiwvae qladivpkkd hlvvvlmgsa sdtshsekia tscrslglnv
      301 elrvssahkg peetlrivre yesvmsnlif vavagrsngl gpvvsgstny pvincppvks
      361 dnmqvdvwss lnlpsglgca tvlypeaaal haatilglgn fmvwsklrvk alnnfitlkk
      421 adkelrgvrn a