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LOCUS XM_017155519 1744 bp mRNA linear INV 09-DEC-2024 mRNA. ACCESSION XM_017155519 VERSION XM_017155519.3 DBLINK BioProject: PRJNA1194641 KEYWORDS RefSeq. SOURCE Drosophila takahashii ORGANISM Drosophila takahashii Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_091683) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 9, 2024 this sequence version replaced XM_017155519.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_030179915.1-RS_2024_12 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 12/07/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..1744 /organism="Drosophila takahashii" /mol_type="mRNA" /strain="IR98-3 E-12201" /db_xref="taxon:29030" /chromosome="X" /sex="female" /tissue_type="Whole fly" /dev_stage="Adult fly" /collected_by="Originally obtained from EHIME-Fly" gene 1..1744 /gene="Paics" /note="PAICS bifunctional enzyme; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 7 Proteins" /db_xref="GeneID:108066828" CDS 233..1528 /gene="Paics" /codon_start=1 /product="bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase" /protein_id="XP_017011008.1" /db_xref="GeneID:108066828" /translation="MSTAATTTTSIEGYKLGKVIIEGKTKQVYDLPEQPGLCLLLSKD RITAGDGVKAHDLAGKAEISNTTNGQVFRLLNEAGIRTAYVKQCGSKAFIARKCQMIP IEWVTRRLATGSFLKRNVGVPEGYRFSPPKQETFFKDDANHDPQWSEEQIVSAKFELN GLVIGQDEVDIMRRTTLLVFEILERAWQTKNCALIDMKVEFGICDDGNIVLADIIDSD SWRLWPAGDKRLMVDKQVYRNLASVTASDLDTVKRNFIWVAEQLADIVPKKDHLVVVL MGSASDTSHSEKIATSCRSLGLNVELRVSSAHKGPEETLRIVREYESVMSNLIFVAVA GRSNGLGPVVSGSTNYPVINCPPVKSDNMQVDVWSSLNLPSGLGCATVLYPEAAALHA ATILGLGNFMVWSKLRVKALNNFITLKKADKELRGVRNA" misc_feature 272..1018 /gene="Paics" /note="Ade5_like 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Ade5; cd01416" /db_xref="CDD:133471" misc_feature order(290..295,299..304,308..310,314..319,344..346, 350..352,479..481,518..520,524..526,530..532,644..646, 830..832,866..871) /gene="Paics" /note="ATP binding site [chemical binding]; other site" /db_xref="CDD:133471" misc_feature order(293..295,299..310,314..316,344..346,380..382, 482..484,515..526,530..532,542..544,548..550,554..556, 566..574,638..640,644..646,662..664,818..826,830..832, 869..871,884..895) /gene="Paics" /note="active site" /db_xref="CDD:133471" misc_feature order(380..382,542..544,548..550,554..556,566..574, 638..640,662..664,818..826,884..895) /gene="Paics" /note="substrate binding site [chemical binding]; other site" /db_xref="CDD:133471" misc_feature 1049..1510 /gene="Paics" /note="phosphoribosylaminoimidazole carboxylase, PurE protein; Region: purE; TIGR01162" /db_xref="CDD:273474" polyA_site 1744 /gene="Paics" /experiment="COORDINATES: polyA evidence [ECO:0006239]" ORIGIN 1 ctcagttgct ttggagcgat tcctcgacgc agacgacgaa cggcggagtt tacggaacgt 61 cagaaaaaca aaaactacaa caaaaaaaca gtggaaagag caagagcaaa gcacaagcga 121 atatcgagca caaagcgaag cgcgcaacac gtgaaacagc agccgtcaat tgggtttcat 181 ttcgattcta attcggattc tgaaagacgc gaaacgcgaa acacgaaacg agatgtccac 241 cgcagccaca acaaccacat cgattgaggg ctacaagctc ggaaaggtca tcatcgaggg 301 caaaaccaag caggtgtacg atctgcccga acagccggga ctttgcctgc tcctcagcaa 361 ggatcgcatc accgcgggcg atggagtcaa ggcccacgat ctggcgggca aggcggagat 421 ctccaatacc accaatggtc aggtctttcg attgctcaac gaggccggaa tacgcaccgc 481 gtatgtgaag cagtgcggct cgaaggcctt catcgcccgc aagtgccaga tgatacccat 541 tgagtgggtg acgcgtcgcc tggccaccgg atcgttcctc aagcgcaatg tcggcgtgcc 601 cgagggctac agattctccc cgccgaaaca ggagaccttc ttcaaggacg acgccaacca 661 cgatccccag tggagcgagg agcagatcgt ctcggccaag ttcgagctga atggcctggt 721 gattggccag gatgaggtgg acatcatgcg caggaccaca ctgctggtct tcgagattct 781 cgagcgggcg tggcagacca agaactgcgc cctcatcgac atgaaggtgg agttcggaat 841 ctgtgacgat ggcaacattg ttctggccga catcattgac tccgattcgt ggcgcctttg 901 gccggccggc gataagcgac tgatggtgga caagcaggtg tatcgcaatc tggcctcggt 961 gacggccagc gatttggaca cggtgaagag gaatttcatt tgggtggccg aacagctggc 1021 cgatattgtg ccaaagaagg atcatctggt tgtggtcctg atgggcagtg cctcggatac 1081 ttcgcacagc gaaaagatag ccaccagctg tcgatcgctg ggcctcaacg tcgagctccg 1141 agtgagttcg gcccacaagg gacccgagga aaccctgcgc attgtccgcg aatacgagtc 1201 ggtgatgagc aacctgatct tcgtggccgt cgccgggcgt tccaatggac tgggtcccgt 1261 cgtctccggc agcaccaact atccggtgat caactgtccg cctgtcaagt cggacaacat 1321 gcaggtggat gtgtggtcca gcctgaattt gccatcgggc ctgggctgtg ccaccgttct 1381 ctatccggag gcggctgccc tgcatgcggc caccattctg ggactgggca acttcatggt 1441 ctggtcgaag ctgcgcgtca aggcgctgaa caactttatc accctcaaga aggccgacaa 1501 ggagctgcgc ggcgtgcgaa acgcttagat gaagaaaggg ggccataaag agtatccttg 1561 aaagatcatc ctcagaatac atcctttgtt aattcttctc ttcgttttta tttttttttt 1621 tgataaccaa aacctttttt atttttgtag tattaagaaa gcacgacttg aactagttgt 1681 atacccttct ggataaggta actcgaaata cctactaata aaaaaattaa atataaaaac 1741 tcaa