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glutathione S-transferase theta-3 [Drosophila takahashii].


LOCUS       XP_017010796             237 aa            linear   INV 09-DEC-2024
ACCESSION   XP_017010796
VERSION     XP_017010796.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017155307.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..237
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..237
                     /product="glutathione S-transferase theta-3"
                     /calculated_mol_wt=27471
     Region          5..80
                     /region_name="GST_N_Theta"
                     /note="GST_N family, Class Theta subfamily; composed of
                     eukaryotic class Theta GSTs and bacterial dichloromethane
                     (DCM) dehalogenase. GSTs are cytosolic dimeric proteins
                     involved in cellular detoxification by catalyzing the
                     conjugation of glutathione (GSH) with...; cd03050"
                     /db_xref="CDD:239348"
     Site            order(11..12,14,17..18,20..22,25,39)
                     /site_type="other"
                     /note="C-terminal domain interface [polypeptide binding]"
                     /db_xref="CDD:239348"
     Site            order(13..14,42..43,56..57,69..70)
                     /site_type="other"
                     /note="GSH binding site (G-site) [chemical binding]"
                     /db_xref="CDD:239348"
     Site            14
                     /site_type="active"
                     /note="sulfate binding site [active]"
                     /db_xref="CDD:239348"
     Site            order(53,65..66,68..69,72)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:239348"
     Region          95..212
                     /region_name="GST_C_Theta"
                     /note="C-terminal, alpha helical domain of Class Theta
                     Glutathione S-transferases; cd03183"
                     /db_xref="CDD:198292"
     Site            order(96..97,100,103..104)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:198292"
     Site            order(106,110..111,114..115,117..118,122,176,179)
                     /site_type="other"
                     /note="substrate binding pocket (H-site) [chemical
                     binding]"
                     /db_xref="CDD:198292"
     CDS             1..237
                     /gene="GstT4"
                     /coded_by="XM_017155307.3:169..882"
                     /db_xref="GeneID:108066689"
ORIGIN      
        1 msqplkfyfd flnqssraly illeaskipf eaipismlkg ehltgefrdn vnrfrklpai
       61 tdhgyqlsen vaifrhlare klvpehwypr rhlgrsride ylawqqtnmg vatteyfqqk
      121 wlvpylqktr padnavnlas kqlehtlnef eqlflnsrkf mlgdnisfad lsaiceidqp
      181 ksigyntfqn rnklarwyet vreelgphyk evlgefetkl kgsgsgqqqg vaqavkq