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cyclin-dependent kinase 7 [Drosophila takahashii].


LOCUS       XP_017009232             353 aa            linear   INV 09-DEC-2024
ACCESSION   XP_017009232
VERSION     XP_017009232.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017153743.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017009232.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..353
                     /product="cyclin-dependent kinase 7"
                     /calculated_mol_wt=39477
     Region          11..308
                     /region_name="STKc_CDK7"
                     /note="Catalytic domain of the Serine/Threonine Kinase,
                     Cyclin-Dependent protein Kinase 7; cd07841"
                     /db_xref="CDD:270833"
     Site            order(18..21,23..24,26,39,41,61,75,91..94,97,99..100,137,
                     139,141..142,144,155,158,160,170,172..175,177,215..216)
                     /site_type="active"
                     /db_xref="CDD:270833"
     Site            order(18,20..24,26,39,41,75,91..94,141..142,160)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270833"
     Site            order(53..55,57,60..61,63..64,67..68,80,82,87,126,
                     129..132,160,162..165,169..170,281,285..287)
                     /site_type="other"
                     /note="CDK/cyclin interface [polypeptide binding]"
                     /db_xref="CDD:270833"
     Site            order(61,99,137,139,158,170,172..175,177,215..216)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270833"
     Site            order(154..165,167..177)
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270833"
     CDS             1..353
                     /gene="Cdk7"
                     /coded_by="XM_017153743.3:91..1152"
                     /db_xref="GeneID:108065659"
ORIGIN      
        1 mlpnpndkkd ryaklsflge gqfaivykar dtvtsqivav kkikkgsred ardginrtal
       61 reikilqelq heniiglvdv fgqlsnvslv fdfmdtdlev iikdtkiilt qanikayaim
      121 tlkgleylhl nwilhrdlkp nnllvnsdgv lkigdfglak sfgspnriyt hhvvtrwyrs
      181 pellfgarqy gtgvdmwavg cilaelmlrv pfmpgdsdld qltrifatlg tpsdaewphl
      241 gklhdylqfr nfpgtpleni ftaagndlih lmrrlfamnp lrrvscqeal smpyfgnkpa
      301 ptvgpklpmp sailaakega npqageekpa lkrklvettv rgnglaqkkr lqf