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caspase-8 isoform X2 [Drosophila takahashii].


LOCUS       XP_017006651             447 aa            linear   INV 09-DEC-2024
ACCESSION   XP_017006651
VERSION     XP_017006651.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017151162.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017006651.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..447
                     /product="caspase-8 isoform X2"
                     /calculated_mol_wt=50263
     Region          205..445
                     /region_name="CASc"
                     /note="Caspase, interleukin-1 beta converting enzyme (ICE)
                     homologues; Cysteine-dependent aspartate-directed
                     proteases that mediate programmed cell death (apoptosis).
                     Caspases are synthesized as inactive zymogens and
                     activated by proteolysis of the peptide...; cl00042"
                     /db_xref="CDD:444667"
     Site            order(242,299,337,344,379..384,388..389)
                     /site_type="other"
                     /note="substrate pocket [chemical binding]"
                     /db_xref="CDD:237997"
     Site            order(298,339)
                     /site_type="active"
                     /db_xref="CDD:237997"
     Site            order(372,375,378,401,409,415,428,433..434,436,439..440)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:237997"
     CDS             1..447
                     /gene="Dredd"
                     /coded_by="XM_017151162.3:237..1580"
                     /db_xref="GeneID:108063889"
ORIGIN      
        1 mtrseadfpp sdllqqyaks rpdawrrhlv ealcivgarq vlrrlgfrwq elrlhylphv
       61 aevalhvhpl lkslyriceq ltlaqsgrlv ldvgekvarq qagdplrfyd ptyleiflld
      121 wltrgslrlg dinaagsdvq lliehlkfnd lqeqakllid tinsnapeaa ppapplvaik
      181 qetqldssas svssasssrr gnalelsrek agivliinqq rfhrnvsedl kqylpskklq
      241 nragtdvdkq rltevfsamn yqveardnvd hldmvqlvrs acdrsllqds lvvcilshgf
      301 eeavygansi alriadienv lcsyetlynk pklliiqacq eealregeen kpfkidvttq
      361 spsqhvnmvr amstvngfsa lrhthsgswf iqglcdaidq hsasehiadi ltivtnevsq
      421 krgkndesmv pkfnssfrqh vyfpprl