translation initiation factor eIF2B subunit epsilon [Drosophila

LOCUS       XP_017006488             671 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_017006488
VERSION     XP_017006488.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017150999.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017006488.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..671
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..671
                     /product="translation initiation factor eIF2B subunit
                     epsilon"
                     /calculated_mol_wt=74385
     Region          9..223
                     /region_name="eIF-2B_epsilon_N"
                     /note="The N-terminal domain of epsilon subunit of the
                     eIF-2B is a subfamily of glycosyltransferase 2; cd04197"
                     /db_xref="CDD:133040"
     Region          326..399
                     /region_name="LbetaH"
                     /note="Left-handed parallel beta-Helix (LbetaH or LbH)
                     domain: The alignment contains 5 turns, each containing
                     three imperfect tandem repeats of a hexapeptide repeat
                     motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing
                     hexapeptide repeats are often enzymes...; cl00160"
                     /db_xref="CDD:469633"
     Site            order(338,340,343,345,355,360,362,372,376..377,379,389,
                     395,397,399)
                     /site_type="other"
                     /note="putative trimer interface [polypeptide binding]"
                     /db_xref="CDD:100061"
     Site            order(372,374..375,379,391,399)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:100061"
     Region          500..660
                     /region_name="W2_eIF2B_epsilon"
                     /note="C-terminal W2 domain of eukaryotic translation
                     initiation factor 2B epsilon; cd11558"
                     /db_xref="CDD:211396"
     CDS             1..671
                     /gene="eIF2Bepsilon"
                     /coded_by="XM_017150999.3:82..2097"
                     /db_xref="GeneID:108063791"
ORIGIN      
        1 maqfekeivq avliadnnvw nfkplsdegs tallplvnvr mldyalialn rsgveevfvy
       61 aslylqdird hikagiatya swsfkmtvhv iggegcrcfg damrdldaka lirghfillg
      121 adtvtnadlr pvleqhkrqa kfdkgtaatl vfkecashgr tgnelliavd rrndrlhyhq
      181 rlrthqkepr yqipldvflg nacvalhhkl ldpqiaigsp smlslfsdnf dfqtrddfvr
      241 gllineelld sriyvallpa aqyahkvnsw payqlvsrdi inrwayplvp dmgvyklqqq
      301 yvfhrdniyk spgaqvskva lhqnvviqag srvdtgslig dsvigancri grncrltnvf
      361 lmadvvvgdn crlehcvvga gatvnencdv sagcvlgags elpagttlar tlvtstpstq
      421 rgeeeavave leslgprafi vsdlttgdpe dsegedllpq qplsipkmgd lpapldeisd
      481 csdlsedded asravtplpd dtniflgevi dsltrgfrek snpdflilei nssryaynms
      541 lkevnfnvvk avfgmqsive pannnvlvai naafkqlgpv vsnyikseea mldclkaled
      601 vyeenplvre kisqivhyly dkdfvsedai qgwfeqldee ehghlrqsla klvawldqss
      661 eeddddeeee d