dual specificity mitogen-activated protein kinase kinase dSOR1

LOCUS       XP_017006130             396 aa            linear   INV 09-DEC-2024
            isoform X1 [Drosophila takahashii].
ACCESSION   XP_017006130
VERSION     XP_017006130.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017150641.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..396
                     /product="dual specificity mitogen-activated protein
                     kinase kinase dSOR1 isoform X1"
                     /calculated_mol_wt=43721
     Region          85..382
                     /region_name="PKc_MEK"
                     /note="Catalytic domain of the dual-specificity Protein
                     Kinase, Mitogen-Activated Protein (MAP)/Extracellular
                     signal-Regulated Kinase (ERK) Kinase; cd06615"
                     /db_xref="CDD:132946"
     Site            order(93..97,101,114,116,146,162..165,168..169,172,209,
                     211..214,216,226..227,230,242..245,247,274,283)
                     /site_type="active"
                     /db_xref="CDD:132946"
     Site            order(93..97,99,101,114,116,146,162..165,168..169,
                     171..172,211,213..214,216,227)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:132946"
     Site            order(96..97,209,211..213,230,242..245,247,274,283)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:132946"
     Site            order(97,116,134,137,146,160,162,227..231,234,238)
                     /site_type="other"
                     /note="noncompetitive inhibitor binding site [chemical
                     binding]"
                     /db_xref="CDD:132946"
     Site            order(100,120..121,156,249,253..256,314,317..318,321..322)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:132946"
     Site            226..247
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:132946"
     CDS             1..396
                     /gene="Dsor1"
                     /coded_by="XM_017150641.3:407..1597"
                     /db_xref="GeneID:108063521"
ORIGIN      
        1 msknklnlvl ppvnteatva aatvaptppf ktpsgtdths llgkpktsid altetlegld
       61 mddterkrik vflsqkekig elsdedlekl gelgsgnggv vmkvrhthth limarklihl
      121 evkpaikkqi lrelkvlhec nfphivgfyg afysdgeisi cmeymdggsl dlilkragri
      181 pesilgritl avlkglsylr dkhaiihrdv kpsnilvnss geikicdfgv sgqlidsman
      241 sfvgtrsyms perlqgthys vqsdiwslgl slvemaigmy pipppntatl esifadnaed
      301 ggqptdepra maifelldyi vnepppkleh kifstefkdf vdiclkkqpd eradlktlls
      361 hpwirkaeve evdisgwvck tmdlppstpk rntspn