dihydropyrimidine dehydrogenase [NADP(+)] [Drosophila takahashii].

LOCUS       XP_017006129            1033 aa            linear   INV 09-DEC-2024
ACCESSION   XP_017006129
VERSION     XP_017006129.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017150640.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017006129.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1033
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1033
                     /product="dihydropyrimidine dehydrogenase [NADP(+)]"
                     /calculated_mol_wt=111229
     Region          55..509
                     /region_name="PRK11749"
                     /note="dihydropyrimidine dehydrogenase subunit A;
                     Provisional; cl46914"
                     /db_xref="CDD:481254"
     Region          529..831
                     /region_name="DHPD_FMN"
                     /note="Dihydropyrimidine dehydrogenase (DHPD) FMN-binding
                     domain. DHPD catalyzes the first step in pyrimidine
                     degradation: the NADPH-dependent reduction of uracil and
                     thymine to the corresponding 5,6-dihydropyrimidines. DHPD
                     contains two FAD, two FMN, and...; cd02940"
                     /db_xref="CDD:239244"
     Site            order(549..550,554..556,558..559,580..582,584..589,607,
                     609,612..614,617,620,624,711..712,736..737,758..759,765,
                     769,773,776..777,801,804,817..818,820..822)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:239244"
     Site            order(571..572,587,606,608,665,667..668,706,732..734)
                     /site_type="active"
                     /db_xref="CDD:239244"
     Site            order(571,587,606,608,665,706,733..734)
                     /site_type="other"
                     /note="FMN binding site [chemical binding]"
                     /db_xref="CDD:239244"
     Site            order(606,608,665,667,733..734)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:239244"
     Region          <888..1011
                     /region_name="NapF"
                     /note="Ferredoxin [Energy production and conversion];
                     COG1145"
                     /db_xref="CDD:440760"
     Region          948..1006
                     /region_name="Fer4_21"
                     /note="4Fe-4S dicluster domain; pfam14697"
                     /db_xref="CDD:434137"
     CDS             1..1033
                     /gene="su(r)"
                     /coded_by="XM_017150640.3:177..3278"
                     /db_xref="GeneID:108063520"
ORIGIN      
        1 msppqllskd spdiedllsl nprvktqcsv vptkqtkenk khwkrnsdha appcttlsnd
       61 fsdikhttls ergaleeaar clkcadapcq kscptqldik sfitsiankn fygaakaifs
      121 dnplgltcgm vcptsdlcvg gcnlqaseag ainigglqqf atevfkkmgv rqrlspqaqa
      181 npllqkvall gggpaslsca tflarlgyrn vtiyerrsyl gglsaaeipq yrlpidavnf
      241 eidlvrnlgv rietgrslgt gdltieglla ngahdavfvg iglpepklnp ifaglepgng
      301 fytsknflpl vsdgskpglc ackaaggglp klhgnvivlg agdtafdcat salrcgarrv
      361 fvvfrkgssg iravpeevel ardercellp ylsprkvivk dglitamefc rteqndqdew
      421 vedeeqtqrl kanfvisafg sgledqdvra alaplqfrge lplvdrvtmq sslpqvflgg
      481 dlagvanttv esvndgkvaa wsihcqlqgl pldtpaalpl fytdidavdi svemcglrfe
      541 npfglasapp ttstamirra feqgwgfvvt ktfgldkdlv tnvsprivrg ttsgykygpq
      601 qgcflnieli sekraeywlk sigelkrdfp ekiviasimc sfneadwtel sikaeqsgad
      661 alelnlscph gmgergmgla cgqdpqlveq isrwvrkavk lpffikltpn itdiasiaea
      721 akrggadggs aintvqglmg lkadstawpa igreqrttyg gvsgnatrpm alkaisdiar
      781 rvpgfpilgi ggidsgeval qfiqagatvl qicssvqnqd ftviedycta lkallylkan
      841 pppvdgpfwd gqspptpvhq kgkpvvrltg egnvtlgffg pyqrqrdlkm aelraekgal
      901 wdaeqqvent spadgalkaa priqdvigaa ldkigpynkl dnkqqkvali dddmcincgk
      961 cymtcadsgy qaiefdkdth iphvnddctg ctlcvsvcpi idcitmvpkk iphvikrgve
     1021 ektfythals qcq