LIM domain kinase 1 isoform X1 [Drosophila takahashii].

LOCUS       XP_017005357            1253 aa            linear   INV 09-DEC-2024
ACCESSION   XP_017005357
VERSION     XP_017005357.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017149868.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017005357.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1253
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1253
                     /product="LIM domain kinase 1 isoform X1"
                     /calculated_mol_wt=137327
     Region          33..88
                     /region_name="LIM1_LIMK"
                     /note="The first LIM domain of LIMK (LIM domain Kinase);
                     cd09364"
                     /db_xref="CDD:188750"
     Site            order(33,36,57,60,63,66,83,86)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:188750"
     Region          95..148
                     /region_name="LIM2_LIMK"
                     /note="The second LIM domain of LIMK (LIM domain Kinase);
                     cd09365"
                     /db_xref="CDD:188751"
     Site            order(95,98,115,118,121,124,144,147)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:188751"
     Region          169..252
                     /region_name="PDZ_LIMK-like"
                     /note="PDZ domain of LIM Kinase (LIMK) family, and related
                     domains; cd06754"
                     /db_xref="CDD:467236"
     Site            order(185..191,202,205,230,234,237..238)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467236"
     Region          389..686
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(389..392,395,397,410,412,441,457..460,504,508..509,
                     511,521..522)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..1253
                     /gene="LIMK1"
                     /coded_by="XM_017149868.3:251..4012"
                     /db_xref="GeneID:108062968"
ORIGIN      
        1 mhhqqrlran ggrggggggs ggsggmgghp plcahcrgql lphpeepivm algqqwhcdc
       61 frcsvceghl hnwyferegl lycredyygr fgdacqqcta vitgpvmvag ehkfhpecfc
      121 ctacgsfige gesyalvers klycgqcygk rscqpadaka rittagkpmh sirlveipkd
      181 atpglrvdgv alddgcptvr iteidvnltn lhigdrilev ngtpvsdssv eqidklirsn
      241 ekmlqltveh dpvqvcrscs qadiqramsa stlilplsts assvevgrer lyktpgepge
      301 qgskarklrq atnasatipp aagaaiamtq lkekercssl sklldeqhqa qqhsahpqly
      361 dlsrtqscrv vqkpqrifra sdlvigeklg egffgkvfkv thrqsgevmv lkelhradee
      421 aqrnfikeva vlrlldhrhv lkfigvlyke kklhmvteyv aggclkelih dpsqslswpq
      481 rvclardiac gmsylhsmni ihrdlnsmnc lvredrsviv adfglarsvd aprlpggvga
      541 sadragggsm tpggygsgan sdaamspsgt lrrsksrqrr qrytvvgnpy wmapemmkgl
      601 kydekvdvfs fgimlceiig rveadpdfmp rnsdfslnqq efrekfcaqc pepfvkvafv
      661 ccdlnpdmrp cfetlhvwll rladdlaaer vpperllhei etfqewyass edalsptsqr
      721 slnnldelvk iaaegeseis pvekekenlv ikpqdipksp hlgkdfspsg erlrdsmrar
      781 rrqrflgaqe errnltpete skeralkkal kkcrpfgerg ylvdlrpgae lqlqdvrdln
      841 tysdvdsscd tslnyhevnn lpapqapqda eevksakeee vldqeganhr laiddmrnrl
      901 hqcrskfehl eeasrrnfnq sqhsmrnffk tppvalkmfq rleheaaaln ggancppppp
      961 rtqrinqtpi fgrknppias svgqrlqhge slenltssgg askqlatpap krskaatttk
     1021 vqpplflpps itssvngnvs tsttttttsc pptapdwlpk khkltlplps phpqaaqrss
     1081 hnhrpatsng kgkvvrpppg rtaqgipasn gvsptrstrp gspskhlaqr htaataqrlt
     1141 naaashqqqq qqqqsarttr lnilspekvh rlgarlsdqk qkmreeaaat aaasavggga
     1201 gagcaaspaa gslnghlqgh rtgasgsanp aggerrrraa ppppvrthfn trc