E3 ubiquitin-protein ligase UBR1 isoform X2 [Drosophila

LOCUS       XP_017004407            1848 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_017004407
VERSION     XP_017004407.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017148918.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_017004407.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1848
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1848
                     /product="E3 ubiquitin-protein ligase UBR1 isoform X2"
                     /calculated_mol_wt=209907
     Region          108..176
                     /region_name="UBR-box_UBR1_like"
                     /note="UBR-box found in ubiquitin-protein ligases,
                     E3-alpha-1 (UBR1), E3-alpha-2 (UBR2), and similar
                     proteins; cd19672"
                     /db_xref="CDD:439070"
     Site            order(109,122,125,134,137,143,146,159,161,173,176)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:439070"
     Region          236..299
                     /region_name="ClpS"
                     /note="ATP-dependent Clp protease adaptor protein ClpS;
                     pfam02617"
                     /db_xref="CDD:460621"
     Region          1180..1238
                     /region_name="RING-H2_UBR1-like"
                     /note="RING finger, H2 subclass, found in
                     ubiquitin-protein ligase E3-alpha-1 (UBR1), E3-alpha-2
                     (UBR2), and similar proteins; cd16482"
                     /db_xref="CDD:438145"
     Region          1356..1824
                     /region_name="PRT6_C"
                     /note="Proteolysis_6 C-terminal; pfam18995"
                     /db_xref="CDD:465944"
     CDS             1..1848
                     /gene="Ubr1"
                     /coded_by="XM_017148918.3:418..5964"
                     /db_xref="GeneID:108062312"
ORIGIN      
        1 mdrydmedvv vappaecssp lkewrlkrqa gtlarsdfie ffkrespkyf dyqtggtetd
       61 tnaltlkcmf kealakeeii dvlvefmlgd npasaleklr legntatvcg kvfkngepty
      121 screcgvdpt cvlcvncfkr sahrfhkykm stsggggccd cgddeawkkd hycqlhlanr
      181 knpleskilt davleraeic fgailafcvn yleiepnasl qcldgnvegg qvdgaqyctv
      241 lyndeshtfd qviqtltkia kckhkdamei vaaidregra vvkcdtfkec ndlktaienq
      301 mipatalltn prnnqslrts vlhigavacq qfalqllgwf qeflvrhylf rktfaelvqr
      361 kqeafcirhi leydvklwkt artcwhrlli sgmlmeydnk mvlaqefsrr yativedfis
      421 ddhdhafsiv slsvqlftvp siahhliahe gifdkllhtf yhvaiekfiq nktlhfskni
      481 asltffkran yilydlryll slkpellnnd lrsgflegcr almrvlnvmq gmesitrqtg
      541 qhmdyepewe cafnlhikla ttisqviewa agdvkllrkl ykmtvralvs nsfivggekt
      601 etrsvaghva nclmydvsvk pvsihlplsr fyagiylhlg ahemtydslq tetealsikl
      661 tpreiiepvl cthamiaqva agmwrrngys llhqlyfyrn vrcrvemldr divclqigas
      721 lmesneflih vlnkfnliaw aqatyetmla espvddefmr qlsmidefle lliviigerw
      781 mpgvsmvtee drlrkeiiql lctksyshse lsralpdgns gnsdnifedv intvavfkkp
      841 vgveskgvye lkehlfeefn vyfyhytked kskaeelqre rrkakkqlvc cpppmlpqlt
      901 paftsmanil qcnvflsict lvmeraldar srsfteshlq kilhllgfai qeelsehypf
      961 lsfyersqhy gileklddla rcprleahrd fvvwtikryk elqakqapsd sqpsgsqqcs
     1021 ggggaseeqp lsseeqarqe keirarlaae rrakimaqmq saqksfmksn aemfaaseke
     1081 tsgstgamew edipaegeea aqddgqeqeq gavalrptvv aclgperkiy qgseanfkci
     1141 lcfencaisr sgpplvssaf vqtsrviftt pnmragpsal hmsccghvmh hscwqeyysn
     1201 eeskeqrrph rnrvalsqah nvefhcpycr tlsntvlpvt ealpafspap sasdsylpld
     1261 sfveimrtla adlgamrdee mcqfpsvagi lrksgvvgdm aqfersvqli rdppklhany
     1321 sdvmaflska llnarqsqqs hlkeqqgtst gtatldpdsi elvpllwdtc sytlqaleiy
     1381 lfevqkplka elpmrhqsca inlvracsrf aasrcnfele lgeiplspsl rlqaeysarl
     1441 lneifnqkgs svlewdcfrk lvplqfgvln lmtaesanqt vipsgsmfdf yilqtmflaq
     1501 ltkavlcfdv dreqakrpgh aeltqlayve qlparirdnm vafyrrynia arvlqaskqk
     1561 qlaeeqqkeg dqqqqqttvv ipcephhlal lleyvqrqms sflrcaclfy rcltdidfpd
     1621 tfptdqpdrf elmcqylgle pqlgvyfdme tvyatmmhsf ashphigrei eqrgqpeevr
     1681 rclqlepclr plprlkplyd dysdlinsvs difcpnnere emktptmcli cgsilcgqsy
     1741 ccqpelgkms vgacthhaha cgaevgiflr irdcqvvylg rgkgcfvqpp yldeygetdq
     1801 glrrgnplrl cqaaysrifl qwlghglhee iarlndntnv avtqwhhm