calpain-C [Drosophila takahashii].

LOCUS       XP_016998589             690 aa            linear   INV 09-DEC-2024
ACCESSION   XP_016998589
VERSION     XP_016998589.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017143100.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_016998589.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..690
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..690
                     /product="calpain-C"
                     /calculated_mol_wt=78035
     Region          7..329
                     /region_name="CysPc"
                     /note="Calpains, domains IIa, IIb; calcium-dependent
                     cytoplasmic cysteine proteinases, papain-like. Functions
                     in cytoskeletal remodeling processes, cell
                     differentiation, apoptosis and signal transduction;
                     cd00044"
                     /db_xref="CDD:238004"
     Site            order(84,242,267)
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:238004"
     Region          346..483
                     /region_name="Calpain_III"
                     /note="Calpain, subdomain III. Calpains are
                     calcium-activated cytoplasmic cysteine proteinases,
                     participate in cytoskeletal remodeling processes, cell
                     differentiation, apoptosis and signal transduction.
                     Catalytic domain and the two calmodulin-like domains
                     are...; cd00214"
                     /db_xref="CDD:238132"
     Region          524..689
                     /region_name="EFh_PEF"
                     /note="The penta-EF hand (PEF) family; cl25352"
                     /db_xref="CDD:355382"
     Region          524..552
                     /region_name="EF-hand motif"
                     /note="EF-hand motif [structural motif]"
                     /db_xref="CDD:320054"
     Site            order(536,543,574,576,578,585,604,606,608,615)
                     /site_type="other"
                     /note="Ca binding site [ion binding]"
                     /db_xref="CDD:320054"
     Site            order(565,567,577,631,634,637..640,650,654,657..658,
                     661..662,665,674..681,683..689)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:320054"
     Region          565..594
                     /region_name="EF-hand motif"
                     /note="EF-hand motif [structural motif]"
                     /db_xref="CDD:320054"
     Region          595..624
                     /region_name="EF-hand motif"
                     /note="EF-hand motif [structural motif]"
                     /db_xref="CDD:320054"
     Region          631..659
                     /region_name="EF-hand motif"
                     /note="EF-hand motif [structural motif]"
                     /db_xref="CDD:320054"
     Region          661..689
                     /region_name="EF-hand motif"
                     /note="EF-hand motif [structural motif]"
                     /db_xref="CDD:320054"
     CDS             1..690
                     /gene="CalpC"
                     /coded_by="XM_017143100.3:1..2073"
                     /db_xref="GeneID:108058403"
ORIGIN      
        1 maskyerils dcraknvlwe dpdfpavqss vfyyqtppft fqwkrivdla mdngsgsgsg
       61 sgsvpvflne taefdvvpgk mgdrwlvscl gllsslrnlf yrvvpadqtl tnahgvfrfr
      121 lwwcgewvev lvddrlptin grlafmqpqa sncfwaalle kaiaklhgsy ealkygtrsd
      181 gltdllggvv rqmpiladni rpqtlkellt ttcivtclad kgatvakknl aermpngilv
      241 nvnyrlssld kvktlmgdsv qlvclkdtfs srpfgekthf lgdwspsskt wervsqvera
      301 rlirqlgpge fwlsfcdfve ifttmevvyl dtetsqdeem lksrplhwkm kmhqgqwkrg
      361 vtaggcrnhe sfhinpqlli avqdqqdlvv alnqhtavep kvigftmynw dgdyllsecl
      421 qkdffknhvs flnsdygntr hvsyhthlea ghyvliptty epaeeahftv rilgtgsfrl
      481 scletqtmil ldpfpalkss esdrcsgvga pgasagqkvk svcqyepvym qladenktin
      541 cfelhellea clpndyikgc anidicrqvi alqdrsgsgr itfqqfktfm vnlkswqgvf
      601 kmytkekagi lraerlrdal cdigfqlstd imncliqryi rkdgtlrlsd fvsavihltt
      661 afnqfhlkny sqvnvievhl hdwiksilsc