NAD-dependent protein deacylase Sirt4 [Drosophila takahashii].

LOCUS       XP_016998563             312 aa            linear   INV 09-DEC-2024
ACCESSION   XP_016998563
VERSION     XP_016998563.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017143074.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..312
                     /product="NAD-dependent protein deacylase Sirt4"
                     /calculated_mol_wt=34843
     Region          38..299
                     /region_name="SIRT4"
                     /note="Eukaryotic and prokaryotic group (class2) which
                     includes human sirtuin SIRT4 and several bacterial
                     homologs; and are members of the SIR2 family of proteins,
                     silent information regulator 2 (Sir2) enzymes which
                     catalyze NAD+-dependent protein/histone...; cd01409"
                     /db_xref="CDD:238700"
     Site            order(55,57..58,65..66,116,134..135,137,152,251,256,
                     278..279,298)
                     /site_type="other"
                     /note="NAD+ binding site [chemical binding]"
                     /db_xref="CDD:238700"
     Site            order(136,152,223,225..229,255..257)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:238700"
     Site            order(160,163,211,214)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:238700"
     CDS             1..312
                     /gene="Sirt4"
                     /coded_by="XM_017143074.3:83..1021"
                     /db_xref="GeneID:108058381"
ORIGIN      
        1 mrvgqllrfr stafrgstar qeyvphhkpv veddikrled flmskpnvlv ltgagistes
       61 gipdyrsegv glyarsnhkp vqhmefvkss avrkrywarn fvgwpkfsat qpnathhala
      121 rfereervqa vvtqnvdrlh skagsrnvve vhgsgyvvkc lsceyridrh efqsilasln
      181 pafkdapdmi rpdgdveipl eyienfqipe ctqcggdlkp eivffgdsvp rsrldeiagm
      241 vynsdgllvl gssllvfsgy rvvlqtkdlk lpvaivnigd tradhladik isakcgdvip
      301 klfdfrsskr as