protein vav isoform X3 [Drosophila takahashii].

LOCUS       XP_016998245            1000 aa            linear   INV 09-DEC-2024
ACCESSION   XP_016998245
VERSION     XP_016998245.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017142756.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_016998245.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1000
                     /product="protein vav isoform X3"
                     /calculated_mol_wt=113200
     Region          19..135
                     /region_name="CH_VAV"
                     /note="calponin homology (CH) domain found in VAV
                     proteins; cd21201"
                     /db_xref="CDD:409050"
     Site            order(20,24,87,89..90,93..94,96,107..115,121,123..124,
                     126..127,130..131,134)
                     /site_type="other"
                     /note="putative actin binding site [polypeptide binding]"
                     /db_xref="CDD:409050"
     Region          427..601
                     /region_name="RhoGEF"
                     /note="RhoGEF domain; pfam00621"
                     /db_xref="CDD:459876"
     Region          625..752
                     /region_name="PH_Vav"
                     /note="Vav pleckstrin homology (PH) domain; cd01223"
                     /db_xref="CDD:269930"
     Region          758..809
                     /region_name="C1_VAV"
                     /note="protein kinase C conserved region 1 (C1 domain)
                     found in VAV proteins; cd20810"
                     /db_xref="CDD:410360"
     Region          823..933
                     /region_name="SH2_Vav_family"
                     /note="Src homology 2 (SH2) domain found in the Vav
                     family; cd09940"
                     /db_xref="CDD:198193"
     Site            order(836,854,881,883)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198193"
     Site            order(882,913)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198193"
     Region          939..992
                     /region_name="SH3"
                     /note="Src Homology 3 domain superfamily; cl17036"
                     /db_xref="CDD:473055"
     Site            order(942,944,948,952,972..973,986,988..989)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212690"
     CDS             1..1000
                     /gene="Vav"
                     /coded_by="XM_017142756.3:488..3490"
                     /db_xref="GeneID:108058170"
ORIGIN      
        1 masnsssnsf ggvagvngdl wrecvawltr ckvippdhka aqadaeiril amtlrdgvll
       61 cnlvihldps smdprefnrk pqmaqflcsk niklfldvch nnfgirdadl feptmlydlt
      121 nfhrvlitls klsqcrkvqq mhpdlvgfnl qlspsershs deaiykdlhs tdlsmrkass
      181 idaasasssa eyydrtsqsg sldensditi engtedtddy iedslsnmcd stiendlled
      241 agvetpllad cdggslrals fdltldvvns dasnavtptp esyaaalgdt aptaaaaaaa
      301 sgippmgrlv sttssssssl lvsesqrlqk aaaavynyrs smasteheya yiyseddekv
      361 yedlcyvtfq akakkpevtt dniacngtgy dhtntkeeev yqdlcalhrt srsqtassts
      421 feqrdyvire lidtesnyld vltalktkfm aplerhlnqd elrlifprir eladihtkfl
      481 dklresltpn akmkmaqvfl efrepfliyg eycscllgai dyladvckkn qiidqlvqkc
      541 erdynvgklq lrdilsvpmq rilkyhllld klvketsplh ddyrslerak eamidvsqyi
      601 nevkrdsdhl viiqkvkdsi fdlnllqngn gsdllqygrl lldgelhika hedqktklry
      661 afvfdkilim vkalhiktgd mqytyrdshn ladyrveqsh srrtlgrdtr fkyqlllark
      721 sgktaftlyl kseherdkwr kalteamesl eppgcrstdh kmeiytfdap ttcrhcskfl
      781 kgrihqgyrc kvcqisvhkg cisstgrckq npvsvpppvc drqlsefnwf agnmdretaa
      841 hrlenrrigt yllrvrpqgp stahetmyal slktddhvik hmkinqensg dsmlyclssr
      901 rhfktivelv syyerndlge nfaglnqslq wpykeviata lydyepkags nqlqlrtdcq
      961 vlvigkdgds kgwwrgkigd tvgyfpkeyv qeqklaseel