protein vav isoform X2 [Drosophila takahashii].

LOCUS       XP_016998244             793 aa            linear   INV 09-DEC-2024
ACCESSION   XP_016998244
VERSION     XP_016998244.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017142755.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..793
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..793
                     /product="protein vav isoform X2"
                     /calculated_mol_wt=91344
     Region          19..135
                     /region_name="CH_VAV"
                     /note="calponin homology (CH) domain found in VAV
                     proteins; cd21201"
                     /db_xref="CDD:409050"
     Site            order(20,24,87,89..90,93..94,96,107..115,121,123..124,
                     126..127,130..131,134)
                     /site_type="other"
                     /note="putative actin binding site [polypeptide binding]"
                     /db_xref="CDD:409050"
     Region          220..394
                     /region_name="RhoGEF"
                     /note="RhoGEF domain; pfam00621"
                     /db_xref="CDD:459876"
     Region          418..545
                     /region_name="PH_Vav"
                     /note="Vav pleckstrin homology (PH) domain; cd01223"
                     /db_xref="CDD:269930"
     Region          551..602
                     /region_name="C1_VAV"
                     /note="protein kinase C conserved region 1 (C1 domain)
                     found in VAV proteins; cd20810"
                     /db_xref="CDD:410360"
     Region          616..726
                     /region_name="SH2_Vav_family"
                     /note="Src homology 2 (SH2) domain found in the Vav
                     family; cd09940"
                     /db_xref="CDD:198193"
     Site            order(629,647,674,676)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198193"
     Site            order(675,706)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198193"
     Region          732..785
                     /region_name="SH3"
                     /note="Src Homology 3 domain superfamily; cl17036"
                     /db_xref="CDD:473055"
     Site            order(735,737,741,745,765..766,779,781..782)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212690"
     CDS             1..793
                     /gene="Vav"
                     /coded_by="XM_017142755.3:488..2869"
                     /db_xref="GeneID:108058170"
ORIGIN      
        1 masnsssnsf ggvagvngdl wrecvawltr ckvippdhka aqadaeiril amtlrdgvll
       61 cnlvihldps smdprefnrk pqmaqflcsk niklfldvch nnfgirdadl feptmlydlt
      121 nfhrvlitls klsqcrkvqq mhpdlvgfnl qlspsershs deaiykdlhs tttdniacng
      181 tgydhtntke eevyqdlcal hrtsrsqtas stsfeqrdyv irelidtesn yldvltalkt
      241 kfmaplerhl nqdelrlifp rireladiht kfldklresl tpnakmkmaq vflefrepfl
      301 iygeycscll gaidyladvc kknqiidqlv qkcerdynvg klqlrdilsv pmqrilkyhl
      361 lldklvkets plhddyrsle rakeamidvs qyinevkrds dhlviiqkvk dsifdlnllq
      421 ngngsdllqy grllldgelh ikahedqktk lryafvfdki limvkalhik tgdmqytyrd
      481 shnladyrve qshsrrtlgr dtrfkyqlll arksgktaft lylkseherd kwrkalteam
      541 esleppgcrs tdhkmeiytf dapttcrhcs kflkgrihqg yrckvcqisv hkgcisstgr
      601 ckqnpvsvpp pvcdrqlsef nwfagnmdre taahrlenrr igtyllrvrp qgpstahetm
      661 yalslktddh vikhmkinqe nsgdsmlycl ssrrhfktiv elvsyyernd lgenfaglnq
      721 slqwpykevi atalydyepk agsnqlqlrt dcqvlvigkd gdskgwwrgk igdtvgyfpk
      781 eyvqeqklas eel