protein vav isoform X1 [Drosophila takahashii].

LOCUS       XP_016998243             963 aa            linear   INV 09-DEC-2024
ACCESSION   XP_016998243
VERSION     XP_016998243.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017142754.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_016998243.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..963
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..963
                     /product="protein vav isoform X1"
                     /calculated_mol_wt=109046
     Region          19..135
                     /region_name="CH_VAV"
                     /note="calponin homology (CH) domain found in VAV
                     proteins; cd21201"
                     /db_xref="CDD:409050"
     Site            order(20,24,87,89..90,93..94,96,107..115,121,123..124,
                     126..127,130..131,134)
                     /site_type="other"
                     /note="putative actin binding site [polypeptide binding]"
                     /db_xref="CDD:409050"
     Region          390..564
                     /region_name="RhoGEF"
                     /note="RhoGEF domain; pfam00621"
                     /db_xref="CDD:459876"
     Region          588..715
                     /region_name="PH_Vav"
                     /note="Vav pleckstrin homology (PH) domain; cd01223"
                     /db_xref="CDD:269930"
     Region          721..772
                     /region_name="C1_VAV"
                     /note="protein kinase C conserved region 1 (C1 domain)
                     found in VAV proteins; cd20810"
                     /db_xref="CDD:410360"
     Region          786..896
                     /region_name="SH2_Vav_family"
                     /note="Src homology 2 (SH2) domain found in the Vav
                     family; cd09940"
                     /db_xref="CDD:198193"
     Site            order(799,817,844,846)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198193"
     Site            order(845,876)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198193"
     Region          902..955
                     /region_name="SH3"
                     /note="Src Homology 3 domain superfamily; cl17036"
                     /db_xref="CDD:473055"
     Site            order(905,907,911,915,935..936,949,951..952)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212690"
     CDS             1..963
                     /gene="Vav"
                     /coded_by="XM_017142754.3:488..3379"
                     /db_xref="GeneID:108058170"
ORIGIN      
        1 masnsssnsf ggvagvngdl wrecvawltr ckvippdhka aqadaeiril amtlrdgvll
       61 cnlvihldps smdprefnrk pqmaqflcsk niklfldvch nnfgirdadl feptmlydlt
      121 nfhrvlitls klsqcrkvqq mhpdlvgfnl qlspsershs deaiykdlhs tdlsmrkass
      181 idaasasssa eyydrtsqsg sldensditi engtedtddy iedslsnmcd stiendlled
      241 agvetpllad cdggslrals fdltldvvns dasnavtptp esyaaalgdt aptaaaaaaa
      301 sgippmgrlv sttssssssl lvsesqrlqk aaaavynyrs smasteheya yiyseddekv
      361 yedlcyvtfq akakkpetas stsfeqrdyv irelidtesn yldvltalkt kfmaplerhl
      421 nqdelrlifp rireladiht kfldklresl tpnakmkmaq vflefrepfl iygeycscll
      481 gaidyladvc kknqiidqlv qkcerdynvg klqlrdilsv pmqrilkyhl lldklvkets
      541 plhddyrsle rakeamidvs qyinevkrds dhlviiqkvk dsifdlnllq ngngsdllqy
      601 grllldgelh ikahedqktk lryafvfdki limvkalhik tgdmqytyrd shnladyrve
      661 qshsrrtlgr dtrfkyqlll arksgktaft lylkseherd kwrkalteam esleppgcrs
      721 tdhkmeiytf dapttcrhcs kflkgrihqg yrckvcqisv hkgcisstgr ckqnpvsvpp
      781 pvcdrqlsef nwfagnmdre taahrlenrr igtyllrvrp qgpstahetm yalslktddh
      841 vikhmkinqe nsgdsmlycl ssrrhfktiv elvsyyernd lgenfaglnq slqwpykevi
      901 atalydyepk agsnqlqlrt dcqvlvigkd gdskgwwrgk igdtvgyfpk eyvqeqklas
      961 eel