mitogen-activated protein kinase kinase kinase 7 isoform X1

LOCUS       XP_016996250             684 aa            linear   INV 09-DEC-2024
            [Drosophila takahashii].
ACCESSION   XP_016996250
VERSION     XP_016996250.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017140761.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_016996250.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..684
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..684
                     /product="mitogen-activated protein kinase kinase kinase 7
                     isoform X1"
                     /calculated_mol_wt=75996
     Region          25..275
                     /region_name="STKc_TAK1"
                     /note="Catalytic domain of the Serine/Threonine Kinase,
                     Transforming Growth Factor beta Activated Kinase-1;
                     cd14058"
                     /db_xref="CDD:270960"
     Site            order(25..29,33,44,46,73,89..92,96,98,140,142,144..145,
                     147,159,162,175..178)
                     /site_type="active"
                     /db_xref="CDD:270960"
     Site            order(25..29,33,44,46,73,89..92,96,140,142,144..145,147,
                     159)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270960"
     Site            order(29,96,98,140,142,144,162,175..178)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270960"
     Site            158..178
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270960"
     Site            order(207..210,215,233..239,272..275)
                     /site_type="other"
                     /note="TAB1 binding site [polypeptide binding]"
                     /db_xref="CDD:270960"
     CDS             1..684
                     /gene="Tak1"
                     /coded_by="XM_017140761.3:840..2894"
                     /db_xref="GeneID:108056782"
ORIGIN      
        1 matasldalq aayvdfselt lrekvghgsy gvvckavwrd klvavkeffa saeqkdieke
       61 vkqlsrvkhv niialhgiss yqqatylime yaeggslhnf lhgkvkpays lahamswarq
      121 caeglaylha mtpkplihrd vkplnllltn kgrnlkicdf gtvadkstmm tnnrgsaawm
      181 apevfegsky tekcdifswa ivlwevlsrk qpfkgidnay tiqwkiykge rppllttcpk
      241 riedlmtacw ktvpedrpsm qyivgvmhei vkdytgadka leytfvnqqi vtkesdgtva
      301 aqsdslssle eelspsstql tpttaananv naiaitetet ttssmtents stssditptn
      361 sgqldnnplf hmvsnrwdai peedsnesrn dsfnltssae atqrletirn gmilmaskpv
      421 eqltvdvepn gfdlsrsess sssthaksdg rerltvtdtk pvimttdlan nnsnnnggsh
      481 ahsngllshv ngrqvtdeel qlqdqeqeia nsldvavdpd edendgteqs laeildpelq
      541 peppipndae sqliyrehrh makeylsvdt nlyyaqdfke klivqmdrne reqkqellrk
      601 ikdkeglqsl ynnlqqqyer lpasrqlsag hhpphqhphs hppshphlhg qqeeiggall
      661 pgsvtggsds veegwvviqp hpna