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rhophilin-2-A isoform X2 [Drosophila takahashii].


LOCUS       XP_016996196             721 aa            linear   INV 09-DEC-2024
ACCESSION   XP_016996196
VERSION     XP_016996196.3
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017140707.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Dec 9, 2024 this sequence version replaced XP_016996196.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..721
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..721
                     /product="rhophilin-2-A isoform X2"
                     /calculated_mol_wt=80842
     Region          40..124
                     /region_name="HR1_Rhophilin-1"
                     /note="Protein kinase C-related kinase homology region 1
                     (HR1) Rho-binding domain of Rhophilin-1; cd11633"
                     /db_xref="CDD:212023"
     Site            order(57,60,63..64,67..68,70..71,74..75,77..78,93..94,97,
                     100..101,104)
                     /site_type="other"
                     /note="putative Rho binding site 1 [polypeptide binding]"
                     /db_xref="CDD:212023"
     Site            order(65..66,68..69,72..73,75..76,79..80,88..89,91)
                     /site_type="other"
                     /note="putative Rho binding site 2 [polypeptide binding]"
                     /db_xref="CDD:212023"
     Region          128..519
                     /region_name="BRO1_Rhophilin"
                     /note="Protein-interacting Bro1-like domain of
                     RhoA-binding protein Rhophilin and related domains;
                     cd09244"
                     /db_xref="CDD:185767"
     Site            order(243,246,259,262..263,307,310..311,326,329..330,503,
                     505,507,509)
                     /site_type="other"
                     /note="putative ESCRT-III binding site"
                     /db_xref="CDD:185767"
     Region          581..645
                     /region_name="PDZ_canonical"
                     /note="canonical PDZ domain; cl49608"
                     /db_xref="CDD:483948"
     Site            order(581..586,594,597,626,630,633..634)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467153"
     CDS             1..721
                     /gene="Rhp"
                     /coded_by="XM_017140707.3:217..2382"
                     /db_xref="GeneID:108056740"
ORIGIN      
        1 mfnlgamdgk tdelaqragk neeneddekl nelsfcfvrg sdpraatcrs klqnrrckln
       61 keinkelrlr agaenlykat snrklrdtva lelsfvnsnl qllkeqlael nssveiyqse
      121 shngimpmip lglketkein fmepfsdfil ehyseepsmy idaiadmtdt rqasktpsrd
      181 algvallfry yntlyyverr ffppdrnlgv yfewydsltg vpscqrtiaf ekactlfnlg
      241 giytqigarh drttergldl avdsflraag ifrhiydtft napsmdlkpq vldvlvslml
      301 sqareclfek lqlqieaigl sefscsfrdl ageaaqishe ynemhkniqa ndthtylpec
      361 waglvpvkae lykafahfyk arsidatdei kvsrnqdkls tesfignsqe vesnfgtsee
      421 aatsnankla hlkealasie eaqrlqrmcr ylknksslte vmkevhsksq eeldrfrlqa
      481 sannieegdl lervveassk ftlsltgpdf tshkvkdpfk rlgpiaifsa rrhwtaprcv
      541 rlqkgsssyh nvpannrcpl dnddeehdgg fnlykeefen fgfhvrgdap viiahveins
      601 ladlggikeg dfiveiagmd vkwyshqqvv qliqscgsal elrvitpmdr nylkplsskg
      661 slstlsaass sgissgfpsp tsiaakpklh lktssssraa gsvsssswnp frrtpslaki
      721 f