lysosomal aspartic protease [Drosophila takahashii].

LOCUS       XP_016995468             410 aa            linear   INV 09-DEC-2024
ACCESSION   XP_016995468
VERSION     XP_016995468.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017139979.2
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_016995468.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..410
                     /product="lysosomal aspartic protease"
                     /calculated_mol_wt=44889
     Region          77..382
                     /region_name="Asp"
                     /note="Eukaryotic aspartyl protease; pfam00026"
                     /db_xref="CDD:394983"
     Site            order(96,98,100,136..138,184)
                     /site_type="active"
                     /note="inhibitor binding site [active]"
                     /db_xref="CDD:133137"
     Site            96..98
                     /site_type="active"
                     /note="catalytic motif [active]"
                     /db_xref="CDD:133137"
     Site            96
                     /site_type="active"
                     /note="Catalytic residue [active]"
                     /db_xref="CDD:133137"
     Site            order(136..139,143..146)
                     /site_type="active"
                     /note="Active site flap [active]"
                     /db_xref="CDD:133137"
     CDS             1..410
                     /gene="Pgcl"
                     /coded_by="XM_017139979.2:1..1233"
                     /db_xref="GeneID:108056253"
ORIGIN      
        1 magsqiqkla flagillilv nlgssalhri pvqrspsfkr shkmivaerd fiqqkytrqy
       61 tangypveql snfdnfqyyg nisigtppqy flvqfdtgss nlwvpssscl seacqdhqty
      121 ygsessthva ngtafsityg tgsvtgylsm dyvgfaglia knqtfgevtt evgtnfvday
      181 fdgilgmgfp slavdgvtpt fqnmvnqgvv qspvfsfflr dngsvvnygg elilggsdps
      241 lyrggltyvd viqaaywkfq tdfikigstl istfdaaiad tgtslivapv aeytqiaqlf
      301 gadsegtfqc tsldsypdlv itingvdfri qakyyiiqen ylcslaiqsi sgqdfwimgd
      361 vflgrfytef dvgnqrlgfa pvnsaisarq lalwqiftla lacgvwklwy