probable methylmalonate-semialdehyde/malonate-semialdehyde

LOCUS       XP_016995447             520 aa            linear   INV 09-DEC-2024
            dehydrogenase [acylating], mitochondrial [Drosophila takahashii].
ACCESSION   XP_016995447
VERSION     XP_016995447.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017139958.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_016995447.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..520
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..520
                     /product="probable
                     methylmalonate-semialdehyde/malonate-semialdehyde
                     dehydrogenase [acylating], mitochondrial"
                     /calculated_mol_wt=55793
     Region          26..502
                     /region_name="ALDH_F6_MMSDH"
                     /note="Methylmalonate semialdehyde dehydrogenase and ALDH
                     family members 6A1 and 6B2; cd07085"
                     /db_xref="CDD:143404"
     Site            order(83,85,89,92,96,129,132..133,142..149,154,157,160,
                     253,257,260,263,265,438,440..441,443..444,447,450..451,
                     453,455..458,467,471,473,487,494..499,501..502)
                     /site_type="other"
                     /note="tetrameric interface [polypeptide binding]"
                     /db_xref="CDD:143404"
     Site            order(169..172,180,195,198,228,245..248,251,269..271,303,
                     403,405,431)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:143404"
     Site            order(172,269,300,303)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143404"
     CDS             1..520
                     /gene="LOC108056242"
                     /coded_by="XM_017139958.3:177..1739"
                     /db_xref="GeneID:108056242"
ORIGIN      
        1 mslvrligae arllakrsys saapttklfi dgkfveskts ewidvhdpat nqvvtrvpka
       61 tqaemqaale snkkafrsws nqsiltrqqv mfklqalike nmgelaknit keqgktlada
      121 egdvlrglqv vehccsipsl qmgetvanva rdmdtyslvl plgvtagvap fnfpamiplw
      181 mfpvaittgn tmllkpserv pgatmllmel lneagcppgv vnvihgqhda vnficdapei
      241 kavsfvgsdq agkyiyerag kngkrvqsnm gaknhgiila dankentlnq lagaafgaag
      301 qrcmalstav fvgdaqswip dlveraqklk vnaghvpgtd vgpvisaasr qrindliesg
      361 vkegaklvld grkisvpgye dgyfvgptil sdvtpsmkcy teeifgpvlv ilnaetldda
      421 igivnanpyg ngtavfttng aaarkfvnei dagqvgvnvp ipvplpmfsf tgtrgsfrgd
      481 hhfygkqgik fytqtktvtq lwretdvtht qaavamptmk