netrin-A isoform X1 [Drosophila takahashii].

LOCUS       XP_016995274             743 aa            linear   INV 09-DEC-2024
ACCESSION   XP_016995274
VERSION     XP_016995274.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017139785.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_016995274.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..743
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..743
                     /product="netrin-A isoform X1"
                     /calculated_mol_wt=81352
     Region          52..267
                     /region_name="LamNT"
                     /note="Laminin N-terminal domain (domain VI); smart00136"
                     /db_xref="CDD:214532"
     Region          334..379
                     /region_name="EGF_Lam"
                     /note="Laminin-type epidermal growth factor-like domain;
                     laminins are the major noncollagenous components of
                     basement membranes that mediate cell adhesion, growth
                     migration, and differentiation; the laminin-type epidermal
                     growth factor-like module occurs in...; cd00055"
                     /db_xref="CDD:238012"
     Site            order(335,337,347,354,356,365)
                     /site_type="active"
                     /note="EGF-like motif [active]"
                     /db_xref="CDD:238012"
     Region          391..448
                     /region_name="EGF_Lam"
                     /note="Laminin-type epidermal growth factor-like domain;
                     laminins are the major noncollagenous components of
                     basement membranes that mediate cell adhesion, growth
                     migration, and differentiation; the laminin-type epidermal
                     growth factor-like module occurs in...; cd00055"
                     /db_xref="CDD:238012"
     Site            order(391,393,400,418,421,430)
                     /site_type="active"
                     /note="EGF-like motif [active]"
                     /db_xref="CDD:238012"
     Region          453..501
                     /region_name="EGF_Lam"
                     /note="Laminin-type epidermal growth factor-like domain;
                     laminins are the major noncollagenous components of
                     basement membranes that mediate cell adhesion, growth
                     migration, and differentiation; the laminin-type epidermal
                     growth factor-like module occurs in...; cd00055"
                     /db_xref="CDD:238012"
     Site            order(454,456,466,473,475,484)
                     /site_type="active"
                     /note="EGF-like motif [active]"
                     /db_xref="CDD:238012"
     Region          567..740
                     /region_name="NTR_netrin-1_like"
                     /note="NTR domain, Netrin-1-like subfamily; The C-terminal
                     NTR domain of netrins is also called domain C in the
                     context of C. elegans netrin UNC-6. Netrins are secreted
                     proteins that function as tropic cues in the direction of
                     axon growth and cell migration...; cd03579"
                     /db_xref="CDD:239634"
     CDS             1..743
                     /gene="NetA"
                     /coded_by="XM_017139785.3:431..2662"
                     /db_xref="GeneID:108056109"
ORIGIN      
        1 mpplaairgl wllavlgilk gipgtagipn dqylkmfpqq appqddlcyd rarepkvcvp
       61 efvnaaldap vvasstcgsm gssanpqryc efqehersch tcdandplrs fparyltdnn
      121 nsnnvtcwrs epvlgsgdnv tltlslgkkf elvyvvlqlc phaprpdsma iykstdhglt
      181 wqpfqfyssq crrlfgrpar qatgrhnehe arcsdltrpm ggsriafrtl egrpsgkdld
      241 sspvmqdwvt atdirvvfhr lqrvgdpqav lsldaghgga svdlaggkys vplanggsgp
      301 tgnnielshe gaggssgsgs glhyaisdfa vggrckcngh askcstdasg qlncecshnt
      361 agrdcerckp fhfdrpwara taketnecke cicnkharqc rfnmeifrls qgvsggvcqn
      421 crhsttgrnc hqckegfyrd ttkplthrkv ckacechpig ssgkicnsts gqcpckdgvt
      481 gltcnrcarg yqqsrshiap cikqpprmin mldtqntape pdepqsspav ggdrsgatgt
      541 aaqsqyyrte ggrecgkcrv stkrlnlnkf ckrdyaimak vigrdtssea aasreaprra
      601 mdpdgedyem dqdqpgsitp adyhypnpns spsdssseve rydlqiqavf krsrpgessg
      661 agnvygmpst ilkrgpmtwi iptkhlecrc pkirvnrsyl ilgrdseapp gylgigphsi
      721 viewkedwyr rmkrfqrrar tca