serine/threonine-protein kinase tousled-like 1 isoform X3

LOCUS       XP_016993572            1295 aa            linear   INV 09-DEC-2024
            [Drosophila takahashii].
ACCESSION   XP_016993572
VERSION     XP_016993572.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017138083.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_016993572.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1295
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1295
                     /product="serine/threonine-protein kinase tousled-like 1
                     isoform X3"
                     /calculated_mol_wt=139186
     Region          <581..>717
                     /region_name="DUF5401"
                     /note="Family of unknown function (DUF5401); pfam17380"
                     /db_xref="CDD:375164"
     Region          967..1234
                     /region_name="STKc_TLK"
                     /note="Catalytic domain of the Serine/Threonine kinase,
                     Tousled-Like Kinase; cd13990"
                     /db_xref="CDD:270892"
     Site            order(970,983,985,1021,1038..1041,1045,1047,1086,1088,
                     1090..1091,1093,1107,1110,1133..1136)
                     /site_type="active"
                     /db_xref="CDD:270892"
     Site            order(1045,1047,1086,1088,1090,1110,1133..1136)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270892"
     Site            order(1106..1118,1123..1136)
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270892"
     CDS             1..1295
                     /gene="Tlk"
                     /coded_by="XM_017138083.3:212..4099"
                     /db_xref="GeneID:108054955"
ORIGIN      
        1 mrskrntsdl gllqrtcivg gksmsagaql qmapqttsal shhhpnqqqq lqppqqqqaq
       61 ppppqqqqhf anhhsaqqqs qqqqeqqnpq qaqqqqaqqq qilpqphlqh lhkhphqlql
      121 hqqqqqlhqq qqhfhqqqqq slqglhqgss npdsnmstgs shsekdvndm lsgggaapgv
      181 aaaaaiqqqh pafapalgmq qppppppqhs nnggemgylt agttttasvt avgkprtpae
      241 rkrkrkmpqt sadeagsggg sggagaavvn nsslkgksla frdmpkvnms lnlgdrlggs
      301 agsgggagga gsggsgagsg sgsgggksar imlpvsdnkk indyfnkqqt gvgvgvpggg
      361 gaggntaglr gshtgggsks pssaqqqqqt tqqqqqqasg vatgggagga aanqqvqvqt
      421 ssayalyppa spqtqtpqqq qqqqpgadfh yvnsskaqqq qqqqqqrqqq qtsnqmvpph
      481 vvvglgghpl slasiqqqqq tplsqqqqqq qqqqqqqqqq lgppttstas vvsthphqlg
      541 slgvvgmvgv gvgvgvnvgv gpplpppppm ampaaiitys katqtevslh elqereaehe
      601 sgkvkldemt rlsdeqkcqi vgnqktidqh kshiakcidv vkkllkekss iekkearqkc
      661 mqnrlrlgqf vtqrvgatfq enwtdgyafq elsrrqeeit aereeidrqk kqlmkkrpae
      721 sgrkrnnnsn qnnqqqqqqq qhqqqqqqqn snsndssqlt ggvvtgpgsd rlggaaggvs
      781 vdsglggnna gaigggavgg gvggggvgsg gvggvggggg rglsrsnstq anqaqllhng
      841 gggsggnvgn sggvgdrlsd rggggglggn dsgscsdsgt flkpdpvsga ytaqeyyeyd
      901 eilklrqnal kkedadlqle meklerernl hirelkriln edqsrfnnhp vlndrylllm
      961 llgkggfsev hkafdlkeqr yvackvhqln kdwkedkkan yikhalreyn ihkaldhprv
     1021 vklydvfeid ansfctvley cdghdldfyl kqhktipere arsiimqvvs alkylneikp
     1081 pvihydlkpg nilltegnvc geikitdfgl skvmddenyn pdhgmdltsq gagtywylpp
     1141 ecfvvgknpp kisskvdvws vgvifyqcly gkkpfghnqs qatileenti lkatevqfsn
     1201 kptvsneaks firgclayrk edrmdvfala rheyiqppip khgrgslnqq qqaqqqqqqq
     1261 qqqqqqqsst sqanstgqts fsahmfgnmn qssss