serine/threonine-protein kinase tousled-like 1 isoform X2

LOCUS       XP_016993571            1296 aa            linear   INV 09-DEC-2024
            [Drosophila takahashii].
ACCESSION   XP_016993571
VERSION     XP_016993571.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017138082.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_016993571.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1296
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1296
                     /product="serine/threonine-protein kinase tousled-like 1
                     isoform X2"
                     /calculated_mol_wt=139543
     Region          <582..>718
                     /region_name="DUF5401"
                     /note="Family of unknown function (DUF5401); pfam17380"
                     /db_xref="CDD:375164"
     Region          968..1235
                     /region_name="STKc_TLK"
                     /note="Catalytic domain of the Serine/Threonine kinase,
                     Tousled-Like Kinase; cd13990"
                     /db_xref="CDD:270892"
     Site            order(971,984,986,1022,1039..1042,1046,1048,1087,1089,
                     1091..1092,1094,1108,1111,1134..1137)
                     /site_type="active"
                     /db_xref="CDD:270892"
     Site            order(1046,1048,1087,1089,1091,1111,1134..1137)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270892"
     Site            order(1107..1119,1124..1137)
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270892"
     CDS             1..1296
                     /gene="Tlk"
                     /coded_by="XM_017138082.3:496..4386"
                     /db_xref="GeneID:108054955"
ORIGIN      
        1 mdqfqtslnp rkqellearf igvrmsagaq lqmapqttsa lshhhpnqqq qlqppqqqqa
       61 qppppqqqqh fanhhsaqqq sqqqqeqqnp qqaqqqqaqq qqilpqphlq hlhkhphqlq
      121 lhqqqqqlhq qqqhfhqqqq qslqglhqgs snpdsnmstg sshsekdvnd mlsgggaapg
      181 vaaaaaiqqq hpafapalgm qqppppppqh snnggemgyl tagttttasv tavgkprtpa
      241 erkrkrkmpq tsadeagsgg gsggagaavv nnsslkgksl afrdmpkvnm slnlgdrlgg
      301 sagsgggagg agsggsgags gsgsgggksa rimlpvsdnk kindyfnkqq tgvgvgvpgg
      361 ggaggntagl rgshtgggsk spssaqqqqq ttqqqqqqas gvatgggagg aaanqqvqvq
      421 tssayalypp aspqtqtpqq qqqqqpgadf hyvnsskaqq qqqqqqqrqq qqtsnqmvpp
      481 hvvvglgghp lslasiqqqq qtplsqqqqq qqqqqqqqqq qlgppttsta svvsthphql
      541 gslgvvgmvg vgvgvgvnvg vgpplppppp mampaaiity skatqtevsl helqereaeh
      601 esgkvkldem trlsdeqkcq ivgnqktidq hkshiakcid vvkkllkeks siekkearqk
      661 cmqnrlrlgq fvtqrvgatf qenwtdgyaf qelsrrqeei taereeidrq kkqlmkkrpa
      721 esgrkrnnns nqnnqqqqqq qqhqqqqqqq nsnsndssql tggvvtgpgs drlggaaggv
      781 svdsglggnn agaigggavg ggvggggvgs ggvggvgggg grglsrsnst qanqaqllhn
      841 ggggsggnvg nsggvgdrls drggggglgg ndsgscsdsg tflkpdpvsg aytaqeyyey
      901 deilklrqna lkkedadlql emeklerern lhirelkril nedqsrfnnh pvlndrylll
      961 mllgkggfse vhkafdlkeq ryvackvhql nkdwkedkka nyikhalrey nihkaldhpr
     1021 vvklydvfei dansfctvle ycdghdldfy lkqhktiper earsiimqvv salkylneik
     1081 ppvihydlkp gnilltegnv cgeikitdfg lskvmddeny npdhgmdlts qgagtywylp
     1141 pecfvvgknp pkisskvdvw svgvifyqcl ygkkpfghnq sqatileent ilkatevqfs
     1201 nkptvsneak sfirgclayr kedrmdvfal arheyiqppi pkhgrgslnq qqqaqqqqqq
     1261 qqqqqqqqss tsqanstgqt sfsahmfgnm nqssss