probable citrate synthase, mitochondrial isoform X2 [Drosophila

LOCUS       XP_016993341             464 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_016993341
VERSION     XP_016993341.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017137852.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_016993341.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..464
                     /product="probable citrate synthase, mitochondrial isoform
                     X2"
                     /calculated_mol_wt=51489
     Region          34..461
                     /region_name="ScCit1-2_like"
                     /note="Saccharomyces cerevisiae (Sc) citrate synthases
                     Cit1-2_like. Citrate synthases (CS) catalyzes the
                     condensation of acetyl coenzyme A (AcCoA) with
                     oxaloacetate (OAA) to form citrate and coenzyme A (CoA),
                     the first step in the citric acid cycle (TCA or...;
                     cd06105"
                     /db_xref="CDD:99858"
     Site            order(72..73,76..82,167,171,174,266,271,274..275,278..279,
                     282..284,288,295..296,299..301,349,446..454)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:99858"
     Site            order(74,266,270,300..303,305,308,342..349,352,357,398,
                     401,403,425,429,446,449)
                     /site_type="active"
                     /db_xref="CDD:99858"
     Site            order(74,300..302,305,308,342..349,352,398,401,403,446)
                     /site_type="other"
                     /note="coenzyme A binding site [chemical binding]"
                     /db_xref="CDD:99858"
     Site            order(74,266,270,301..302,342..343,345..349,357,401,429)
                     /site_type="other"
                     /note="citrylCoA binding site [chemical binding]"
                     /db_xref="CDD:99858"
     Site            order(266,270,302..303,348..349,357,403,425,429,449)
                     /site_type="other"
                     /note="oxalacetate/citrate binding site [chemical
                     binding]"
                     /db_xref="CDD:99858"
     Site            order(302,348,403)
                     /site_type="active"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:99858"
     CDS             1..464
                     /gene="kdn"
                     /coded_by="XM_017137852.3:201..1595"
                     /db_xref="GeneID:108054783"
ORIGIN      
        1 mslyrisark lteaqklpnv gayvrmisad gkslrdvlta kvpqeqervk nfrkqhgatk
       61 mgettidmmy ggmrgikalv tetsvldade girfrglsip ecqkvlpaad ggteplpegl
      121 fwllltgevp tksqvqqlsr ewaeraalpq hvvtmlnnmp ttlhpmsqfa aavtalnhds
      181 kfakaysdgv hkskyweyvy edsmdliakl pvvaatiycn tyrggkgsrs idssldwsan
      241 fvkmlgydna pftelmrlyl tihsdheggn vsahtvhlvg salsdpylsf aaglnglagp
      301 lhglanqevl vwlrklqkea gnnpseeqlk eyiwktlksg qvvpgyghav lrktdprytc
      361 qrefalkhlp ddetfqlvsk iykvvppilt etgkvknpwp nvdahsgvll qyygmkemny
      421 ytvlfgvsra lgvlaslvwd ralglpierp ksfstdllvk mvqk