frizzled-4 [Drosophila takahashii].

LOCUS       XP_016993339             698 aa            linear   INV 09-DEC-2024
ACCESSION   XP_016993339
VERSION     XP_016993339.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017137850.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_016993339.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..698
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..698
                     /product="frizzled-4"
                     /calculated_mol_wt=76200
     Region          42..168
                     /region_name="CRD_FZ4"
                     /note="Cysteine-rich Wnt-binding domain of the frizzled 4
                     (Fz4) receptor; cd07448"
                     /db_xref="CDD:143557"
     Site            order(52,54..56,58..60)
                     /site_type="other"
                     /note="putative Wnt binding site [polypeptide binding]"
                     /db_xref="CDD:143557"
     Region          222..558
                     /region_name="7tmF_Frizzled_SMO"
                     /note="class F frizzled/smoothened family, member of the
                     7-transmembrane G protein-coupled receptor superfamily;
                     cd13951"
                     /db_xref="CDD:320089"
     Site            order(223,232,285,413,418,420,429,510,513..514,521,526,
                     529..530)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:320089"
     Region          231..256
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:320089"
     Region          268..289
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:320089"
     Region          321..347
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:320089"
     Region          388..404
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:320089"
     Region          426..455
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:320089"
     Region          481..508
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:320089"
     Region          519..544
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:320089"
     CDS             1..698
                     /gene="fz4"
                     /coded_by="XM_017137850.3:879..2975"
                     /db_xref="GeneID:108054781"
ORIGIN      
        1 mkhawmiypl llillhsrct ratsggspgs assssppemp afrqcetiri emcrkigyne
       61 tsmpnlvghe mqtdveytlq tfaplieydc ssqlklflca ayvpmctpka pvhaigpcrs
      121 lcesvrirch pvlqgfgfpw ppaldcerfp rennhetmcm egpgevhqpq qdqdpyglpg
      181 qplggglpgg klpldcsgla kshlyvrlpr sgrcaplcea dilftpaekh laeiwvstwa
      241 yaacglalva tgcllasdgs rlasakwsrl lsplvwchnm vtlgwavrfv vgrtgtacgt
      301 dpqapsesll svdglsnasc asvflmryyf gmaacawwav lclgwhrdir rhspdskghv
      361 aipanfggsp skrsgvksaq qdlsqnnfvc fvawglpafq taavivarfv dadellgacf
      421 vgnqsdkalq ilvatpvfcy wifgsmnlis gylvhcrtke ilrssntlsl qqqlqqlsah
      481 sssgigvflf iyglscalll laviyefani dvwlgsgdtd tplwpfllra fmelmlgicc
      541 fawvlgpsis tlykrqvkmv kqptaaagga ggaggadghs ssrgshaacn stvvsyhsvr
      601 psmasaplpq spyklkaags islhqmsnys lgrsmqhqqq qrsshsphhh hqqqlqqhhh
      661 hhhhsssshr lyyppgsyas qkysyyphlq hygdetll