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cathepsin B [Drosophila takahashii].


LOCUS       XP_016993113             340 aa            linear   INV 09-DEC-2024
ACCESSION   XP_016993113
VERSION     XP_016993113.2
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_017137624.3
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 18, 2021 this sequence version replaced XP_016993113.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..340
                     /product="cathepsin B"
                     /calculated_mol_wt=37196
     Region          24..64
                     /region_name="Propeptide_C1"
                     /note="Peptidase family C1 propeptide; pfam08127"
                     /db_xref="CDD:462365"
     Region          88..336
                     /region_name="Peptidase_C1A_CathepsinB"
                     /note="Cathepsin B group; composed of cathepsin B and
                     similar proteins, including tubulointerstitial nephritis
                     antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like
                     cysteine peptidase which is expressed in all tissues and
                     functions primarily as an...; cd02620"
                     /db_xref="CDD:239111"
     Site            order(109,115,284,306)
                     /site_type="active"
                     /db_xref="CDD:239111"
     Site            order(160..161,258,282,285,332)
                     /site_type="active"
                     /note="S2 subsite [active]"
                     /db_xref="CDD:239111"
     CDS             1..340
                     /gene="CtsB"
                     /coded_by="XM_017137624.3:221..1243"
                     /db_xref="GeneID:108054582"
ORIGIN      
        1 mkllllvata asvaalcage psllsdefie vvrskaktwt vgrnfdasvt eehirrlmgv
       61 hpdahkfala ekrevlgely tavdgdlpee fdarkqwpnc ptigeirdqg scgscwafga
      121 veamsdrvci hsggkvnfhf saddlvscch tcgfgcnggf pgaawsywtr kgivsggpyg
      181 snqgcrpyei spcehhvngt rppcahgggt pkcqhvcqss ytvdyakdkh fgsksysvkr
      241 nvreiqeeim tngpvegaft vyedlilykd gvyqhehgke lgghairilg wgvwgdekip
      301 ywlignswnt dwgdhgffri lrgqdhcgie ssisaglpkl