5'-AMP-activated protein kinase catalytic subunit alpha-2 [Stomoxys

LOCUS       XP_013116298             561 aa            linear   INV 02-SEP-2023
            calcitrans].
ACCESSION   XP_013116298
VERSION     XP_013116298.1
DBLINK      BioProject: PRJNA1009844
DBSOURCE    REFSEQ: accession XM_013260844.2
KEYWORDS    RefSeq.
SOURCE      Stomoxys calcitrans (stable fly)
  ORGANISM  Stomoxys calcitrans
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Muscoidea; Muscidae; Stomoxys.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_081555) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963082655.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/29/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..561
                     /organism="Stomoxys calcitrans"
                     /db_xref="taxon:35570"
                     /chromosome="4"
     Protein         1..561
                     /product="5'-AMP-activated protein kinase catalytic
                     subunit alpha-2"
                     /calculated_mol_wt=62927
     Region          24..279
                     /region_name="STKc_AMPK_alpha"
                     /note="Catalytic domain of the Alpha subunit of the
                     Serine/Threonine Kinase, AMP-activated protein kinase;
                     cd14079"
                     /db_xref="CDD:270981"
     Site            order(33..37,41,54,56,88,104..107,111,113..114,116,
                     149..150,152,154..155,157,167..168,171,185..189,191,
                     221..224)
                     /site_type="active"
                     /db_xref="CDD:270981"
     Site            order(33..36,41,54,56,88,104..107,111,154..155,157,
                     167..168)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270981"
     Site            order(111,113..114,116,150,152,154,171,185..189,191,
                     221..224)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270981"
     Site            167..189
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270981"
     Site            order(175..180,199..200,202,205,265)
                     /site_type="other"
                     /note="heterotrimer interface [polypeptide binding]"
                     /db_xref="CDD:270981"
     Region          296..360
                     /region_name="UBA_AID_AMPKalpha"
                     /note="UBA-like autoinhibitory domain (AID) found in
                     vertebrate 5'-AMP-activated protein kinase catalytic alpha
                     (AMPKalpha) subunits; cd14336"
                     /db_xref="CDD:270521"
     Region          436..559
                     /region_name="AMPKA_C"
                     /note="C-terminal regulatory domain of 5'-AMP-activated
                     protein kinase (AMPK) alpha catalytic subunit; cd12122"
                     /db_xref="CDD:213378"
     Site            order(437..442,449..450,454,457..458,461,465..467,
                     469..473,476..478,489,493..497,502..503,505..508,543,
                     545..546,548..550,552..553,556..557)
                     /site_type="other"
                     /note="beta subunit interface [polypeptide binding]"
                     /db_xref="CDD:213378"
     Site            order(481,543..544,546..547,550)
                     /site_type="other"
                     /note="gamma subunit interface [polypeptide binding]"
                     /db_xref="CDD:213378"
     CDS             1..561
                     /gene="LOC106093713"
                     /coded_by="XM_013260844.2:473..2158"
                     /db_xref="GeneID:106093713"
ORIGIN      
        1 manprasvaa evvhhsgpqp lvkighyllg ntlgtgtfgk vkigehqmtk hkvavkilnr
       61 qkiksldvvg kirreiqnlk lfrhphiikl yqvistptdi fmimeyvsgg elfdyivkhg
      121 klqehearrf fqqiisgvdy chrhmivhrd lkpenllldh nrhvkiadfg lsnmmldgef
      181 lrtscgspny aapevisgkl yagpevdiws cgvilyallc gtlpfddehv ptlfrkiksg
      241 ifpipeylnk tvvnlvcqml qvdplkrani eeikkhewfq kdlpsylfps sieqdsnvid
      301 tyavsevctk fgvkeqevhn allsgdphdq laiayhliid nkrfadeaak teinnffvag
      361 spppaahspn eapdvnfgvg sssgnstpgr tsltpsmkph periaplrer qlamavqaqg
      421 ggafpektar gtpikrakwh lgirsqskpn dimlevyram kaldyewkii npyhvrvrrq
      481 nikngiyskm slqlyqvdak sylldfkslt ndeveqgddv ilesltpppl stsgimppqp
      541 tghhtmeffe mcaaliiqla r