pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

LOCUS       XP_013107483             399 aa            linear   INV 02-SEP-2023
            isoform X2 [Stomoxys calcitrans].
ACCESSION   XP_013107483
VERSION     XP_013107483.1
DBLINK      BioProject: PRJNA1009844
DBSOURCE    REFSEQ: accession XM_013252029.2
KEYWORDS    RefSeq.
SOURCE      Stomoxys calcitrans (stable fly)
  ORGANISM  Stomoxys calcitrans
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Muscoidea; Muscidae; Stomoxys.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_081555) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963082655.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/29/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Stomoxys calcitrans"
                     /db_xref="taxon:35570"
                     /chromosome="4"
     Protein         1..399
                     /product="pyruvate dehydrogenase E1 component subunit
                     alpha, mitochondrial isoform X2"
                     /calculated_mol_wt=43928
     Region          34..391
                     /region_name="TPP_enzymes"
                     /note="Thiamine pyrophosphate (TPP) enzyme family,
                     TPP-binding module; found in many key metabolic enzymes
                     which use TPP (also known as thiamine diphosphate) as a
                     cofactor. These enzymes include, among others, the E1
                     components of the pyruvate, the acetoin and...; cl01629"
                     /db_xref="CDD:470272"
     Site            order(92,144,169..170,201,203..206,209,213,217,232..235,
                     249,299,303)
                     /site_type="other"
                     /note="tetramer interface [polypeptide binding]"
                     /db_xref="CDD:238958"
     Site            order(122..123,169,171,199..202,229,231,295)
                     /site_type="other"
                     /note="TPP-binding site [chemical binding]"
                     /db_xref="CDD:238958"
     Site            order(164,166,168,173,176..177,180..181,183..184,187,
                     206..207,213..214,217)
                     /site_type="other"
                     /note="heterodimer interface [polypeptide binding]"
                     /db_xref="CDD:238958"
     Site            order(290..296,298..308,317..319)
                     /site_type="phosphorylation"
                     /note="phosphorylation loop region [posttranslational
                     modification]"
                     /db_xref="CDD:238958"
     CDS             1..399
                     /gene="LOC106087108"
                     /coded_by="XM_013252029.2:144..1343"
                     /db_xref="GeneID:106087108"
ORIGIN      
        1 mlrqlnrage fpkvvkqlqk ssavagtqks nnyateatvq vqrpyklhrl dqgpettvki
       61 tkdqaltyyt qmqtirrlet sagnlykeki irgfchlysg qeacavgmra amrdvdniis
      121 ayrvhgwtyl mgvsplgvla eltgrqsgca kgkggsmhmy cpnfyggngi vgaqvplgag
      181 valackykgn ggmclalygd gaanqgqvfe aynmaylwkl pvifvcennn ygmgtsaera
      241 ssntdyytrg dalpgiwvdg mdvlavrsat efaidyvnkn gplvmetnty rysghsmsdp
      301 gtsyrtreei qevrqkrdpi tsfkemcieq glittdevka idtkvrkevd eataqakada
      361 elplsglwtd vysqclepki rncvehnikh vqqnkganh