ras GTPase-activating protein 1 isoform X3 [Stomoxys calcitrans].

LOCUS       XP_013105349             904 aa            linear   INV 02-SEP-2023
ACCESSION   XP_013105349
VERSION     XP_013105349.1
DBLINK      BioProject: PRJNA1009844
DBSOURCE    REFSEQ: accession XM_013249895.2
KEYWORDS    RefSeq.
SOURCE      Stomoxys calcitrans (stable fly)
  ORGANISM  Stomoxys calcitrans
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Muscoidea; Muscidae; Stomoxys.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_081555) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963082655.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/29/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Stomoxys calcitrans"
                     /db_xref="taxon:35570"
                     /chromosome="4"
     Protein         1..904
                     /product="ras GTPase-activating protein 1 isoform X3"
                     /calculated_mol_wt=103036
     Region          21..116
                     /region_name="SH2_Nterm_RasGAP"
                     /note="N-terminal Src homology 2 (SH2) domain found in Ras
                     GTPase-activating protein 1 (GAP); cd10353"
                     /db_xref="CDD:198216"
     Site            order(41,60,81,83)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198216"
     Site            order(82,108)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198216"
     Region          133..191
                     /region_name="SH3_RasGAP"
                     /note="Src Homology 3 domain of Ras GTPase-Activating
                     Protein 1; cd11788"
                     /db_xref="CDD:212722"
     Region          202..276
                     /region_name="SH2_Cterm_RasGAP"
                     /note="C-terminal Src homology 2 (SH2) domain found in Ras
                     GTPase-activating protein 1 (GAP); cd10354"
                     /db_xref="CDD:198217"
     Site            order(210,228,249,251)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198217"
     Site            order(250,276)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198217"
     Region          329..434
                     /region_name="PH_RASA1"
                     /note="RAS p21 protein activator (GTPase activating
                     protein) 1 Pleckstrin homology (PH) domain; cd13260"
                     /db_xref="CDD:270080"
     Region          449..572
                     /region_name="C2_Ras_p21A1"
                     /note="C2 domain present in RAS p21 protein activator 1
                     (RasA1); cd08400"
                     /db_xref="CDD:176045"
     Region          570..904
                     /region_name="RasGAP"
                     /note="Ras GTPase Activating Domain; cl02569"
                     /db_xref="CDD:470620"
     Site            order(605,641,643,645..646,648,651,655,750,758..759,
                     762..763,766,787,790..791,794,798,800,805..806)
                     /site_type="other"
                     /note="RAS interface [polypeptide binding]"
                     /db_xref="CDD:213340"
     CDS             1..904
                     /gene="LOC106085572"
                     /coded_by="XM_013249895.2:399..3113"
                     /db_xref="GeneID:106085572"
ORIGIN      
        1 mqslqkqlrd wpkrlsvtlg gerpaiiapp esewyhgrld rysaesrlrg sskvgsylvr
       61 esdrkpgsyv lsyfgrtgin hfritavcgd fyiggrqfis lsdlvgyyts csdllkrerl
      121 vfpvpppepv ndkkrvvail pytkmpdtde lsfqkgdiff vhndmgdgwl wvtahrtgeq
      181 gmifrelved ldpaidpntv fpwfhpnctk neavdmlvka gpgsflvrps dnspgdyslf
      241 fhinnqiqrf riekkgvryl mggrtfecld avinryrkeq iveghclshp vvngtqpeys
      301 qqyvvekaae kiyatlrecr dqiglkkikg ikhhghlnkk sdktakwkql yfalisecse
      361 thlcfydnpk ktkpkglidl scaylyqchd slwerpycfq iveralpcla tvtylcapsq
      421 esyvewinal kaqcasqlsk aqkkvprlre lrsltlhile ahrlpfklvp hpycsislnq
      481 vkvgktkvki apdpvweeef vlddvppdvv sltitlisrg krgkdsevae ltidlaslkn
      541 gheteewyql tgmtpmgewg slrlrmryld dlimpceeys plqqlllepe lysvkalael
      601 chndrvplat sllrvfrhek retelirvlc qaeiarenet ttlfrgasla ttlmdlymrt
      661 ectgflqaai setiqrimds kqsaelnptk mdvnddacsn aefllqildl vthsiftspe
      721 acprsvrfic nclqkavvak wpterlvrtr vvsgfiflrl lcpsllnprq fglvnetppa
      781 aatrslvmva kclqnlanli efggkeqyme vvnpfilknk ermivfldql smvtdpnppp
      841 gwnseqssnq spqdtgrela tlhhicvsyl pelqelsnil sikklvtvtd mltkhklkyr
      901 emis