ras GTPase-activating protein 1 isoform X2 [Stomoxys calcitrans].

LOCUS       XP_013105341             982 aa            linear   INV 02-SEP-2023
ACCESSION   XP_013105341
VERSION     XP_013105341.1
DBLINK      BioProject: PRJNA1009844
DBSOURCE    REFSEQ: accession XM_013249887.2
KEYWORDS    RefSeq.
SOURCE      Stomoxys calcitrans (stable fly)
  ORGANISM  Stomoxys calcitrans
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Muscoidea; Muscidae; Stomoxys.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_081555) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963082655.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/29/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..982
                     /organism="Stomoxys calcitrans"
                     /db_xref="taxon:35570"
                     /chromosome="4"
     Protein         1..982
                     /product="ras GTPase-activating protein 1 isoform X2"
                     /calculated_mol_wt=111406
     Region          100..194
                     /region_name="SH2_Nterm_RasGAP"
                     /note="N-terminal Src homology 2 (SH2) domain found in Ras
                     GTPase-activating protein 1 (GAP); cd10353"
                     /db_xref="CDD:198216"
     Site            order(119,138,159,161)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198216"
     Site            order(160,186)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198216"
     Region          211..269
                     /region_name="SH3_RasGAP"
                     /note="Src Homology 3 domain of Ras GTPase-Activating
                     Protein 1; cd11788"
                     /db_xref="CDD:212722"
     Region          280..354
                     /region_name="SH2_Cterm_RasGAP"
                     /note="C-terminal Src homology 2 (SH2) domain found in Ras
                     GTPase-activating protein 1 (GAP); cd10354"
                     /db_xref="CDD:198217"
     Site            order(288,306,327,329)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198217"
     Site            order(328,354)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198217"
     Region          407..512
                     /region_name="PH_RASA1"
                     /note="RAS p21 protein activator (GTPase activating
                     protein) 1 Pleckstrin homology (PH) domain; cd13260"
                     /db_xref="CDD:270080"
     Region          527..650
                     /region_name="C2_Ras_p21A1"
                     /note="C2 domain present in RAS p21 protein activator 1
                     (RasA1); cd08400"
                     /db_xref="CDD:176045"
     Region          648..982
                     /region_name="RasGAP"
                     /note="Ras GTPase Activating Domain; cl02569"
                     /db_xref="CDD:470620"
     Site            order(683,719,721,723..724,726,729,733,828,836..837,
                     840..841,844,865,868..869,872,876,878,883..884)
                     /site_type="other"
                     /note="RAS interface [polypeptide binding]"
                     /db_xref="CDD:213340"
     CDS             1..982
                     /gene="LOC106085572"
                     /coded_by="XM_013249887.2:1114..4062"
                     /db_xref="GeneID:106085572"
ORIGIN      
        1 mflhsfksaf stassssssn tsllmdtstv dqlmryrnst gnanttpsik tsatsgahve
       61 aliahaeddd ehddhhlltd ldnvdaiiny vikmqyicse rpaiiappes ewyhgrldry
      121 saesrlrgss kvgsylvres drkpgsyvls yfgrtginhf ritavcgdfy iggrqfisls
      181 dlvgyytscs dllkrerlvf pvpppepvnd kkrvvailpy tkmpdtdels fqkgdiffvh
      241 ndmgdgwlwv tahrtgeqgm ifrelvedld paidpntvfp wfhpnctkne avdmlvkagp
      301 gsflvrpsdn spgdyslffh innqiqrfri ekkgvrylmg grtfecldav inryrkeqiv
      361 eghclshpvv ngtqpeysqq yvvekaaeki yatlrecrdq iglkkikgik hhghlnkksd
      421 ktakwkqlyf alisecseth lcfydnpkkt kpkglidlsc aylyqchdsl werpycfqiv
      481 eralpclatv tylcapsqes yvewinalka qcasqlskaq kkvprlrelr sltlhileah
      541 rlpfklvphp ycsislnqvk vgktkvkiap dpvweeefvl ddvppdvvsl titlisrgkr
      601 gkdsevaelt idlaslkngh eteewyqltg mtpmgewgsl rlrmrylddl impceeyspl
      661 qqlllepely svkalaelch ndrvplatsl lrvfrhekre telirvlcqa eiarenettt
      721 lfrgaslatt lmdlymrtec tgflqaaise tiqrimdskq saelnptkmd vnddacsnae
      781 fllqildlvt hsiftspeac prsvrficnc lqkavvakwp terlvrtrvv sgfiflrllc
      841 psllnprqfg lvnetppaaa trslvmvakc lqnlanlief ggkeqymevv npfilknker
      901 mivfldqlsm vtdpnpppgw nseqssnqsp qdtgrelatl hhicvsylpe lqelsnilsi
      961 kklvtvtdml tkhklkyrem is