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ras GTPase-activating protein 1 isoform X1 [Stomoxys calcitrans].


LOCUS       XP_013105336             983 aa            linear   INV 02-SEP-2023
ACCESSION   XP_013105336
VERSION     XP_013105336.1
DBLINK      BioProject: PRJNA1009844
DBSOURCE    REFSEQ: accession XM_013249882.2
KEYWORDS    RefSeq.
SOURCE      Stomoxys calcitrans (stable fly)
  ORGANISM  Stomoxys calcitrans
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Muscoidea; Muscidae; Stomoxys.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_081555) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963082655.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/29/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Stomoxys calcitrans"
                     /db_xref="taxon:35570"
                     /chromosome="4"
     Protein         1..983
                     /product="ras GTPase-activating protein 1 isoform X1"
                     /calculated_mol_wt=110934
     Region          93..195
                     /region_name="SH2_Nterm_RasGAP"
                     /note="N-terminal Src homology 2 (SH2) domain found in Ras
                     GTPase-activating protein 1 (GAP); cd10353"
                     /db_xref="CDD:198216"
     Site            order(120,139,160,162)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198216"
     Site            order(161,187)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198216"
     Region          212..270
                     /region_name="SH3_RasGAP"
                     /note="Src Homology 3 domain of Ras GTPase-Activating
                     Protein 1; cd11788"
                     /db_xref="CDD:212722"
     Region          281..355
                     /region_name="SH2_Cterm_RasGAP"
                     /note="C-terminal Src homology 2 (SH2) domain found in Ras
                     GTPase-activating protein 1 (GAP); cd10354"
                     /db_xref="CDD:198217"
     Site            order(289,307,328,330)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198217"
     Site            order(329,355)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198217"
     Region          408..513
                     /region_name="PH_RASA1"
                     /note="RAS p21 protein activator (GTPase activating
                     protein) 1 Pleckstrin homology (PH) domain; cd13260"
                     /db_xref="CDD:270080"
     Region          528..651
                     /region_name="C2_Ras_p21A1"
                     /note="C2 domain present in RAS p21 protein activator 1
                     (RasA1); cd08400"
                     /db_xref="CDD:176045"
     Region          649..983
                     /region_name="RasGAP"
                     /note="Ras GTPase Activating Domain; cl02569"
                     /db_xref="CDD:470620"
     Site            order(684,720,722,724..725,727,730,734,829,837..838,
                     841..842,845,866,869..870,873,877,879,884..885)
                     /site_type="other"
                     /note="RAS interface [polypeptide binding]"
                     /db_xref="CDD:213340"
     CDS             1..983
                     /gene="LOC106085572"
                     /coded_by="XM_013249882.2:399..3350"
                     /db_xref="GeneID:106085572"
ORIGIN      
        1 mqslqkqlrd wpkrlsvtlg dlmrlgnvdv viqkdklgsp iggsddgnla afggginnfv
       61 ggmntaavgg gggggvafdm gdlqqeldqd efdgmnling erpaiiappe sewyhgrldr
      121 ysaesrlrgs skvgsylvre sdrkpgsyvl syfgrtginh fritavcgdf yiggrqfisl
      181 sdlvgyytsc sdllkrerlv fpvpppepvn dkkrvvailp ytkmpdtdel sfqkgdiffv
      241 hndmgdgwlw vtahrtgeqg mifrelvedl dpaidpntvf pwfhpnctkn eavdmlvkag
      301 pgsflvrpsd nspgdyslff hinnqiqrfr iekkgvrylm ggrtfeclda vinryrkeqi
      361 veghclshpv vngtqpeysq qyvvekaaek iyatlrecrd qiglkkikgi khhghlnkks
      421 dktakwkqly falisecset hlcfydnpkk tkpkglidls caylyqchds lwerpycfqi
      481 veralpclat vtylcapsqe syvewinalk aqcasqlska qkkvprlrel rsltlhilea
      541 hrlpfklvph pycsislnqv kvgktkvkia pdpvweeefv lddvppdvvs ltitlisrgk
      601 rgkdsevael tidlaslkng heteewyqlt gmtpmgewgs lrlrmryldd limpceeysp
      661 lqqlllepel ysvkalaelc hndrvplats llrvfrhekr etelirvlcq aeiarenett
      721 tlfrgaslat tlmdlymrte ctgflqaais etiqrimdsk qsaelnptkm dvnddacsna
      781 efllqildlv thsiftspea cprsvrficn clqkavvakw pterlvrtrv vsgfiflrll
      841 cpsllnprqf glvnetppaa atrslvmvak clqnlanlie fggkeqymev vnpfilknke
      901 rmivfldqls mvtdpnpppg wnseqssnqs pqdtgrelat lhhicvsylp elqelsnils
      961 ikklvtvtdm ltkhklkyre mis