E3 ubiquitin-protein ligase HECW2 isoform X3 [Stomoxys calcitrans].

LOCUS       XP_013103284             428 aa            linear   INV 02-SEP-2023
ACCESSION   XP_013103284
VERSION     XP_013103284.1
DBLINK      BioProject: PRJNA1009844
DBSOURCE    REFSEQ: accession XM_013247830.2
KEYWORDS    RefSeq.
SOURCE      Stomoxys calcitrans (stable fly)
  ORGANISM  Stomoxys calcitrans
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Muscoidea; Muscidae; Stomoxys.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_081555) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963082655.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/29/2023
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Stomoxys calcitrans"
                     /db_xref="taxon:35570"
                     /chromosome="4"
     Protein         1..428
                     /product="E3 ubiquitin-protein ligase HECW2 isoform X3"
                     /calculated_mol_wt=50022
     Region          70..426
                     /region_name="HECTc"
                     /note="HECT domain; C-terminal catalytic domain of a
                     subclass of Ubiquitin-protein ligase (E3). It binds
                     specific ubiquitin-conjugating enzymes (E2), accepts
                     ubiquitin from E2, transfers ubiquitin to substrate lysine
                     side chains, and transfers additional...; cd00078"
                     /db_xref="CDD:238033"
     Site            order(76,107,118,179,355,390..391,394..398,418,425)
                     /site_type="active"
                     /note="catalytic cleft [active]"
                     /db_xref="CDD:238033"
     Site            order(207,210..211,213..214,217,225,227,231,233,239,244,
                     261,265)
                     /site_type="active"
                     /note="E2 interaction site [active]"
                     /db_xref="CDD:238033"
     CDS             1..428
                     /gene="LOC106084257"
                     /coded_by="XM_013247830.2:59..1345"
                     /db_xref="GeneID:106084257"
ORIGIN      
        1 melmwhfclf eqeimsyvpi eerspqgspv lnsrmmqrap ppfrrdfeak lrsfyrkles
       61 kgygqgphkl klqirrthll edafrrimsa nkkdlqrgrl avlwdteegl dyggpsreff
      121 fllsrelfnp yyglfeysan dtytvqvspl safvdnchdw frfsgrvlgl alvhqyllda
      181 fftrpfykal lrlpvalsdl esldsefhqs lqwirdndig tgidlgltfc vteellgrvv
      241 erelkpggkn iivneknkke ylermikwrl ergvqeqtes lvrgfyevvd srlvsvfdar
      301 elelviagta eidindwrln teyrsgyhdn hqviiwfwqv iekftneqrl rllqfvtgts
      361 sipyegfsal rgstgprrfc iekwgkpnal prahtcfnrl dlppyptpel lyeklllave
      421 etntfgie